Destabilizing influences in apoptosis: sowing the seeds of IAP destruction

被引：95

作者：

Martin, SJ ^{[1
]}

机构：

[1] Univ Dublin Trinity Coll, Dept Genet, Mol Cell Biol Lab, Dublin 2, Ireland

来源：

CELL | 2002年 / 109卷 / 07期

关键词：

D O I：

10.1016/S0092-8674(02)00802-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Inhibitor of apoptosis proteins (IAPs) can block apoptosis through interactions with members of the caspase family of cysteine proteases. Recent developments suggest that ubiquitin-proteasome mediated destruction of the Drosophila IAP, DIAP1, is a key event during the initiation of programmed cell death in the fly.

引用

页码：793 / 796

页数：4

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