Moving toward a gene therapy for Huntington's disease

[1] Brain-derived neurotrophic factor-mediated protection of striatal neurons in an excitotoxic rat model of Huntington's disease, as demonstrated by adenoviral gene transfer [J]. HUMAN GENE THERAPY, 1999, 10 (18) : 2987 - 2997

[2] Transcriptional dysregulation of coding and non-coding genes in cellular models of Huntington's disease [J]. BIOCHEMICAL SOCIETY TRANSACTIONS, 2009, 37 : 1270 - 1275

[3] Patient-Specific Neutralizing Antibody Responses to Herpes Simplex Virus Are Attributed to Epitopes on gD, gB, or Both and Can Be Type Specific [J]. JOURNAL OF VIROLOGY, 2015, 89 (18) : 9213 - 9231

[4] An in vitro perspective on the molecular mechanisms underlying mutant huntingtin protein toxicity [J]. CELL DEATH & DISEASE, 2012, 3 : e382 - e382

[5] Colby DW, 2004, P NATL ACAD SCI USA, V101, P17616, DOI 10.1073/pnas.0408134101

[6] Sustained striatal ciliary neurotrophic factor expression negatively affects behavior and gene expression in normal and R6/1 mice [J]. JOURNAL OF NEUROSCIENCE RESEARCH, 2008, 86 (08) : 1748 - 1757

[7] Recombinant variant of ciliary neurotrophic factor for weight loss in obese adults - A randomized, dose-ranging study [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2003, 289 (14): : 1826 - 1832

[8] Cerebrospinal fluid-based kinetic biomarkers of axonal transport in monitoring neurodegeneration [J]. JOURNAL OF CLINICAL INVESTIGATION, 2012, 122 (09) : 3159 - 3169

[9] Feigin A, 2001, J NUCL MED, V42, P1591

[10] Synthetic zinc finger repressors reduce mutant huntingtin expression in the brain of R6/2 mice [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (45) : E3136 - E3145

[1] Brain-derived neurotrophic factor-mediated protection of striatal neurons in an excitotoxic rat model of Huntington's disease, as demonstrated by adenoviral gene transfer [J]. HUMAN GENE THERAPY, 1999, 10 (18) : 2987 - 2997

[2] Transcriptional dysregulation of coding and non-coding genes in cellular models of Huntington's disease [J]. BIOCHEMICAL SOCIETY TRANSACTIONS, 2009, 37 : 1270 - 1275

[3] Patient-Specific Neutralizing Antibody Responses to Herpes Simplex Virus Are Attributed to Epitopes on gD, gB, or Both and Can Be Type Specific [J]. JOURNAL OF VIROLOGY, 2015, 89 (18) : 9213 - 9231

[4] An in vitro perspective on the molecular mechanisms underlying mutant huntingtin protein toxicity [J]. CELL DEATH & DISEASE, 2012, 3 : e382 - e382

[5] Colby DW, 2004, P NATL ACAD SCI USA, V101, P17616, DOI 10.1073/pnas.0408134101

[6] Sustained striatal ciliary neurotrophic factor expression negatively affects behavior and gene expression in normal and R6/1 mice [J]. JOURNAL OF NEUROSCIENCE RESEARCH, 2008, 86 (08) : 1748 - 1757

[7] Recombinant variant of ciliary neurotrophic factor for weight loss in obese adults - A randomized, dose-ranging study [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2003, 289 (14): : 1826 - 1832

[8] Cerebrospinal fluid-based kinetic biomarkers of axonal transport in monitoring neurodegeneration [J]. JOURNAL OF CLINICAL INVESTIGATION, 2012, 122 (09) : 3159 - 3169

[9] Feigin A, 2001, J NUCL MED, V42, P1591

[10] Synthetic zinc finger repressors reduce mutant huntingtin expression in the brain of R6/2 mice [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (45) : E3136 - E3145