Sustained remission of CIDP associated with Evans syndrome

被引:42
作者
Knecht, H [1 ]
Baumberger, M
Tobòn, A
Steck, A
机构
[1] Swiss Parapleg Ctr, Inst Clin Res, CH-6207 Luzern, Switzerland
[2] Swiss Parapleg Ctr, Med Clin, CH-6207 Luzern, Switzerland
[3] Univ Hosp, Dept Neurol, Basel, Switzerland
关键词
D O I
10.1212/01.WNL.0000134606.50529.C7
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
A patient with chronic inflammatory demyelinating polyneuropathy (CIDP) developed Evans syndrome (hemolytic anemia/thrombocytopenia) 17 months after onset of symptoms despite different immunomodulatory treatments. A therapeutic approach with the chimeric monoclonal anti-CD20 antibody rituximab induced substantial improvement of CIDP and hematologic recovery. The patient remains in sustained remission 17 months after completion of therapy. Rituximab may represent a successful therapy in otherwise refractory CIDP.
引用
收藏
页码:730 / 732
页数:3
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