Analysis of 24-Hour Blood Pressure Profile, Heart Rate Variability and Carotid Atherosclerosis in Hypertensive Patients Among Native and Nonnative Population Living in Yamalo-Nenets Autonomous District

Objective: to study special characteristics of the course of arterial hypertension (AH) among native and nonnative population of Yamalo-Nenets autonomous district. Material and methods. We examined 100 residents of Far North with AH (men and women aged 21-55, mean age 44.08 +/- 1.15 years). All patients were divided into 2 equal groups by 50 subjects: group I consisted of representatives of native and group II - nonnative population. Examination was carried out in outpatient clinic in Salekhard and included 24-hour ambulatory blood pressure monitoring (ABPM), registration of heart rate variability, duplex scanning of brachiocephalic arteries, and assessment of blood lipid profile. The groups were matched by age, gender and disease duration. Results. Analysis of heart rate variability detected significant degree of strain of regulatory systems in most patients of both groups. According to results of ABPM "non-dipper" patients prevailed in group I compared to group II (p=0.01). Common carotid artery intima-media complex was significantly greater compared to normal value in all patients; it was thicker in group I (p<0.03), but number of carotid artery stenoses was similar in both groups. No dyslipoproteinemia was detected. Conclusion. Compared with group of representatives of nonnative (adopted) population group of native subjects with AH was characterized by greater carotid intima media thickness and prevalence of "non-dipper" patients.