Update of Intravitreal Steroids for the Treatment of Diabetic Macular Edema

被引:24
作者
Bandello, Francesco [1 ]
Preziosa, Chiara [1 ]
Querques, Giuseppe [1 ]
Lattanzio, Rosangela [1 ]
机构
[1] Univ Vita Salute, San Raffaele Sci Inst, Dept Ophthalmol, IT-20132 Milan, Italy
关键词
Diabetic macular edema; Intravitreal pharmacotherapies; Steroids; Triamcinolone acetonide; Fluocinolone acetonide; Dexamethasone implant; ENDOTHELIAL GROWTH-FACTOR; DRUG-DELIVERY SYSTEM; RANDOMIZED CONTROLLED-TRIAL; ACETONIDE VITREOUS INSERTS; FLUOCINOLONE ACETONIDE; TRIAMCINOLONE ACETONIDE; DEXAMETHASONE IMPLANT; LASER TREATMENT; CLINICAL-TRIAL; RANIBIZUMAB;
D O I
10.1159/000362764
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Diabetic macular edema is considered the most important factor related to visual impairment in patients with diabetic retinopathy. Together with the use of grid and focal laser photocoagulation, today the intravitreal administration of pharmacotherapies represents the standard of care for the treatment of this complication: anti-vascular endothelium growth factor agents and steroids are the drugs currently used for this aim. Differently from laser therapy, which prevents visual deterioration, the intravitreal approach allows the promotion of visual recovery. However, the intravitreal injections require to be repeated with high frequency, and this carries the risk of drug- and procedure-related adverse effects. (C) 2014 S. Karger AG, Basel
引用
收藏
页码:89 / 96
页数:8
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