Vibrio cholerae O139 in Calcutta, 1992-1998:: Incidence, antibiograms, and genotypes

被引：50

作者：

Basu, A

Garg, P

Datta, S

Chakraborty, S

Bhattacharya, T

Khan, A

Ramamurthy, T

Bhattacharya, SK

Yamasaki, S

Takeda, Y

Nair, GB

机构：

[1] Natl Inst Cholera & Enter Dis, Calcutta 700010, W Bengal, India

[2] Natl Inst Infect Dis, Tokyo, Japan

[3] Int Med Ctr Japan, Tokyo, Japan

来源：

EMERGING INFECTIOUS DISEASES | 2000年 / 6卷 / 02期

关键词：

D O I：

10.3201/eid0602.000206

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report results of surveillance for cholera caused by Vibrio cholerae O139 from September 1992, when it was first identified, to December 1998. V. cholerae O139 dominated as the causative agent of cholera in Calcutta during 1992-93 and 1996-97, while the O1 strains dominated during the rest of the period. Dramatic shifts in patterns of resistance to cotrimoxazole, neomycin, and streptomycin were observed. Molecular epidemiologic studies showed clonal diversity among the O139 strains and continuous emergence of new epidemic clones, reflected by changes in the structure, organization, and location of the CTX prophages in the V. cholerae O139 chromosome.

引用

页码：139 / 147

页数：9

共 28 条

[1] Heterogeneity in the organization of the CTX genetic element in strains of Vibrio cholerae O139 Bengal isolated from Calcutta, India and Dhaka, Bangladesh and its possible link to the dissimilar incidence of O139 cholera in the two locales [J].