Functional analysis of atypical mutations in exons 13 and 15 of JAK2 gene in myeloproliferative neoplasms

被引：1

作者：

Luo, Ming ^{[1
]}

Tian, Tingting ^{[1
]}

Zhang, Yaofang ^{[1
]}

Zhang, Xialin ^{[1
]}

Xie, Juan ^{[1
]}

Xu, Jing ^{[1
]}

Ren, Weixiao ^{[1
]}

Tian, Chuchu ^{[1
]}

Wang, Jiaxuan ^{[1
]}

Tan, Yanhong ^{[1
]}

Wang, Hongwei ^{[1
]}

Chen, Xiuhua ^{[1
]}

机构：

[1] Shanxi Med Univ, Hosp 2, Inst Hematol, 382 Wuyi Rd, Taiyuan 030001, Peoples R China

来源：

INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY | 2021年 / 43卷 / 03期

基金：

中国国家自然科学基金;

关键词：

atypical mutation; JAK2; myeloproliferative neoplasms; PSEUDOKINASE DOMAIN;

D O I：

10.1111/ijlh.13398

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：E110 / E113

页数：4

共 10 条

[1] The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia [J].

Arber, Daniel A. ;

Orazi, Attilio ;

Hasserjian, Robert ;

Thiele, Jurgen ;

Borowitz, Michael J. ;

Le Beau, Michelle M. ;

Bloomfield, Clara D. ;

Cazzola, Mario ;

Vardiman, James W. .

BLOOD, 2016, 127 (20) :2391-2405

[2] Crystal structures of the JAK2 pseudokinase domain and the pathogenic mutant V617F [J].

Bandaranayake, Rajintha M. ;

Ungureanu, Daniela ;

Shan, Yibing ;

Shaw, David E. ;

Silvennoinen, Olli ;

Hubbard, Stevan R. .

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2012, 19 (08) :754-759

[3] Whole-exome sequencing identifies novel MPL and JAK2 mutations in triple-negative myeloproliferative neoplasms [J].

Feenstra, Jelena D. Milosevic ;

Nivarthi, Harini ;

Gisslinger, Heinz ;

Leroy, Emilie ;

Rumi, Elisa ;

Chachoua, Ilyas ;

Bagienski, Klaudia ;

Kubesova, Blanka ;

Pietra, Daniela ;

Gisslinger, Bettina ;

Milanesi, Chiara ;

Jaeger, Roland ;

Chen, Doris ;

Berg, Tiina ;

Schalling, Martin ;

Schuster, Michael ;

Bock, Christoph ;

Constantinescu, Stefan N. ;

Cazzola, Mario ;

Kralovics, Robert .

BLOOD, 2016, 127 (03) :325-332

[4] ATP binding to the pseudokinase domain of JAK2 is critical for pathogenic activation [J].

Hammaren, Henrik M. ;

Ungureanu, Daniela ;

Grisouard, Jean ;

Skoda, Radek C. ;

Hubbard, Stevan R. ;

Silvennoinen, Olli .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 112 (15) :4642-4647

[5] Assessing the Performance of the MM/PBSA and MM/GBSA Methods. 1. The Accuracy of Binding Free Energy Calculations Based on Molecular Dynamics Simulations [J].

Hou, Tingjun ;

Wang, Junmei ;

Li, Youyong ;

Wang, Wei .

JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2011, 51 (01) :69-82

[6] Mutation Profile of JAK2 Transcripts in Patients with Chronic Myeloproliferative Neoplasias [J].

Ma, Wanlong ;

Kantarjian, Hagop ;

Zhang, Xi ;

Yeh, Chen-Hsiung ;

Zhang, Zhong J. ;

Verstovsek, Srdan ;

Albitar, Maher .

JOURNAL OF MOLECULAR DIAGNOSTICS, 2009, 11 (01) :49-53

[7] ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB [J].

Maier, James A. ;

Martinez, Carmenza ;

Kasavajhala, Koushik ;

Wickstrom, Lauren ;

Hauser, Kevin E. ;

Simmerling, Carlos .

JOURNAL OF CHEMICAL THEORY AND COMPUTATION, 2015, 11 (08) :3696-3713

[8] Influence of water-protein hydrogen bonding on the stability of Trp-cage miniprotein. A comparison between the TIP3P and TIP4P-Ew water models [J].

Paschek, Dietmar ;

Day, Ryan ;

Garcia, Angel E. .

PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2011, 13 (44) :19840-19847

[9] Pathogenesis of myeloproliferative neoplasms [J].

Skoda, Radek C. ;

Duek, Adrian ;

Grisouard, Jean .

EXPERIMENTAL HEMATOLOGY, 2015, 43 (08) :599-608

[10] Development and testing of a general amber force field [J].

Wang, JM ;

Wolf, RM ;

Caldwell, JW ;

Kollman, PA ;

Case, DA .

JOURNAL OF COMPUTATIONAL CHEMISTRY, 2004, 25 (09) :1157-1174

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