Analysis of the Heterogeneities of First and Second Order of Cellulose Derivatives: A Complex Challenge

被引：9

作者：

Mischnick, Petra ^{[1
]}

Voiges, Kristin ^{[1
]}

Cuers-Dammann, Julia ^{[1
]}

Unterieser, Inga ^{[1
]}

Sudwischer, Patrick ^{[1
,2
]}

Wubben, Anika ^{[1
]}

Hashemi, Payam ^{[1
,3
]}

机构：

[1] Tech Univ Carolo Wilhelmina Braunschweig, Inst Food Chem, Schleinitzstr 20, D-38106 Braunschweig, Germany

[2] Res Inst Feed Technol, Frickenmuhle 1A, D-38110 Braunschweig, Germany

[3] Tech Univ Dresden, Chair Funct Mat, Stadtgutstr 59, D-01217 Dresden, Germany

来源：

POLYSACCHARIDES | 2021年 / 2卷 / 04期

关键词：

polysaccharide derivatives; cellulose ethers; substituent distribution; heterogeneity of first and second order; polysaccharide fractionation; SODIUM CARBOXYMETHYL CELLULOSE; SUBSTITUENT DISTRIBUTION; METHYL CELLULOSE; POLYMER-CHAIN; STARCH; PATTERNS; METHYLCELLULOSES; FRACTIONATION; DEPOLYMERIZATION; DERIVATIZATION;

D O I：

10.3390/polysaccharides2040051

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

The complexity of the substituent distribution in polysaccharide derivatives is discussed and defined. The challenges regarding analytical characterization that results from various interrelated categories of distributions, including molecular weight, chemical composition, and microstructure, are outlined. Due to these convoluted levels of complexity, results should always be interpreted with carefulness. Various analytical approaches which have been applied to starch and cellulose derivatives are recapped, including enzymatic, mass spectrometric, and chromatographic methods. The relation of heterogeneities of first and second order among and along the polysaccharide chains is addressed. Finally, examples of own analytical work on cellulose ethers are presented, including the MS analysis of methyl cellulose (MC) blends and fractionation studies of fully esterified MC, especially its 4-methoxybenzoates by gradient HPLC on normal phase. Preparative fractionation according to the degree of substitution (DS) allows follow-up analysis in order to get more detailed information on the substituent distribution in such sub-fractions.

引用

页码：843 / 865

页数：23

共 74 条

[1] Comprehensive analysis of the substituent distribution in the glucosyl units and along the polymer chain of hydroxyethylmethyl celluloses and statistical evaluation [J].