Is gastric cancer preventable?

被引：71
作者：
Correa, P [1 ]
机构：
[1] Louisiana State Univ, Hlth Sci Ctr, Dept Pathol, New Orleans, LA 70112 USA
来源：
GUT | 2004年 / 53卷 / 09期
关键词：
D O I：
10.1136/gut.2004.039834
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Gastric cancer is a major health burden worldwide and prevention is the most promising strategy to control the disease. The available scientific evidence indicates that curing Helicobacter pylori infection results in a modest retardation of the precancerous process but does not prevent all cancers. Individuals at the highest risk should be cured of their infection and monitored endoscopically to detect dysplasia and "early'" cancer, amenable to successful treatment.
引用
收藏
页码：1217 / 1219
页数：3
相关论文
共 20 条
  • [1] Chemoprevention of gastric dysplasia:: Randomized trial of antioxidant supplements and anti-Helicobacter pylori therapy
    Correa, P
    Fontham, ETH
    Bravo, JC
    Bravo, LE
    Ruiz, B
    Zarama, G
    Realpe, JL
    Malcom, GT
    Li, D
    Johnson, WD
    Mera, R
    [J]. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2000, 92 (23): : 1881 - 1888
  • [2] CORREA P, 1975, LANCET, V2, P58
  • [3] The importance of interleukin 1β in Helicobacter pylori associated disease
    El-Omar, EM
    [J]. GUT, 2001, 48 (06) : 743 - 747
  • [4] Interleukin-1 polymorphisms associated with increased risk of gastric cancer
    El-Omar, EM
    Carrington, M
    Chow, WH
    McColl, KEL
    Bream, JH
    Young, HA
    Herrera, J
    Lissowska, J
    Yuan, CC
    Rothman, N
    Lanyon, G
    Martin, M
    Fraumeni, JF
    Rabkin, CS
    [J]. NATURE, 2000, 404 (6776) : 398 - 402
  • [5] FABER K, 1900, DERMAT Z KLIN MED, V40, P98
  • [6] Figueiredo C, 2002, J NATL CANCER I, V94, P1680, DOI 10.1093/jnci/94.22.1680
  • [7] International Agency for Research on Cancer, 1994, IARC MON EV CARC RIS, V61
  • [8] JARVI O, 1951, ACTA PATHOL MIC SC, V29, P26
  • [9] Factors predicting progression of gastric intestinal metaplasia:: results of a randomised trial on Helicobacter pylori eradication
    Leung, WK
    Lin, SR
    Ching, JYL
    To, KF
    Ng, EKW
    Chan, FKL
    Lau, JYW
    Sung, JJY
    [J]. GUT, 2004, 53 (09) : 1244 - 1249
  • [10] Helicobacter pylori eradication and gastric preneoplastic conditions:: A randomized, double-blind, placebo-controlled trial
    Ley, C
    Mohar, A
    Guarner, J
    Herrera-Goepfert, R
    Figueroa, LS
    Halperin, D
    Johnstone, I
    Parsonnet, J
    [J]. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2004, 13 (01) : 4 - 10
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