Antileukemic Activity and Tolerability of ASP2215 80mg and Greater in FLT3 Mutation-Positive Subjects with Relapsed or Refractory Acute Myeloid Leukemia: Results from a Phase 1/2, Open-Label, Dose-Escalation/Dose-Response Study

被引：1

作者：

Altman, Jessica K. ^{[1
]}

Perl, Alexander E. ^{[2
]}

Cortes, Jorge E. ^{[3
]}

Levis, Mark J. ^{[4
]}

Smith, Catherine C. ^{[5
]}

Litzow, Mark R. ^{[6
]}

Baer, Maria R. ^{[7
]}

Claxton, David F. ^{[8
]}

Erba, Harry P. ^{[9
,10
]}

Gill, Stanley C. ^{[11
]}

Goldberg, Stuart L. ^{[12
]}

Jurcic, Joseph G. ^{[13
]}

Larson, Richard A. ^{[14
]}

Lui, Charles ^{[11
]}

Ritchie, Ellen K. ^{[15
]}

Sargent, Briana ^{[11
]}

Schiller, Gary J. ^{[16
]}

Spira, Alexander I. ^{[17
]}

Strickland, Stephen A. ^{[18
]}

Tibes, Raoul ^{[19
]}

Ustun, Celalettin ^{[20
]}

Wang, Eunice S. ^{[21
]}

Stuart, Robert K. ^{[22
]}

Baldus, Claudia D. ^{[23
]}

Rollig, Christoph ^{[24
]}

Neubauer, Andreas ^{[25
]}

Martinelli, Giovanni ^{[26
]}

Bahceci, Erkut ^{[11
]}

机构：

[1] Northwestern Univ, Chicago, IL 60611 USA

[2] Univ Penn, Abramson Comprehens Canc Ctr, Philadelphia, PA 19104 USA

[3] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA

[4] Johns Hopkins Univ, Baltimore, MD USA

[5] Univ Calif San Francisco, Dept Med, San Francisco, CA USA

[6] Mayo Clin, Div Hematol, Rochester, MN USA

[7] Univ Maryland, Greenebaum Canc Ctr, Baltimore, MD 21201 USA

[8] Penn State Milton S Hershey Med Ctr, Hershey, PA USA

[9] Univ Alabama Birmingham, Birmingham, AL USA

[10] UAB Comprehens Canc Ctr, Birmingham, AL USA

[11] Astellas Pharma US Inc, Northbrook, IL USA

[12] Hackensack Univ, Med Ctr, Hackensack, NJ USA

[13] Columbia Univ, Med Ctr, New York, NY USA

[14] Univ Chicago, Chicago, IL 60637 USA

[15] Weill Cornell Med Ctr, New York, NY USA

[16] Univ Calif Los Angeles, Med Ctr, Los Angeles, CA 90024 USA

[17] Virginia Canc Specialists, Fairfax, VA USA

[18] Vanderbilt Univ, Med Ctr, Dept Med, Div Hematol & Oncol, Nashville, TN USA

[19] Mayo Clin Scottsdale Arizona, Scottsdale, AZ USA

[20] Univ Minnesota, Div Hematol Oncol & Transplantat, Minneapolis, MN USA

[21] Roswell Pk Canc Inst, Dept Med, Buffalo, NY 14263 USA

[22] Med Univ S Carolina, Charleston, SC 29425 USA

[23] Charite, Berlin, Germany

[24] Univ Klinikum TU, Dresden, Germany

[25] Univ Klinikum Giessen & Marburg, Marburg, Germany

[26] Seragnoli Inst Hematol, Bologna, Italy

来源：

BLOOD | 2015年 / 126卷 / 23期

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页数：4