Paediatric kidney transplants from donors aged 1 year and under: an analysis of the Australian and New Zealand Dialysis and Transplant Registry from 1963 to 2018

被引：0

作者：

Yao, Jinna ^{[1
,2
,3
]}

Clayton, Philip A. ^{[4
,5
,6
]}

Wyburn, Kate ^{[3
,7
]}

Choksi, Harsham ^{[3
]}

Cavazzoni, Elena ^{[8
,9
]}

Tovmassian, David ^{[1
]}

Lau, Howard M. H. ^{[1
,11
,12
]}

Allen, Richard ^{[1
,3
]}

Yuen, Lawrence ^{[1
,3
]}

Laurence, Jerome M. ^{[3
,10
]}

Lam, Vincent W. T. ^{[1
]}

Pleass, Henry C. C. ^{[1
,3
]}

机构：

[1] Westmead Hosp, Natl Pancreas Transplant Unit, Sydney, NSW 2145, Australia

[2] Westmead Hosp, Dept Urol, Sydney, NSW, Australia

[3] Univ Sydney, Sch Med, Fac Med & Hlth, Camperdown, NSW, Australia

[4] Univ Adelaide, Dept Med, Adelaide, SA, Australia

[5] South Australian Hlth & Med Res Inst SAHMRI, Australia & New Zealand Dialysis & Transplant ANZ, Adelaide, SA, Australia

[6] Royal Adelaide Hosp, Cent & Northern Adelaide Renal & Transplantat Ser, Adelaide, SA, Australia

[7] Royal Prince Alfred Hosp, Dept Renal Med, Sydney, NSW, Australia

[8] NSW Organ & Tissue Donat Serv, Sydney, NSW, Australia

[9] Childrens Hosp Westmead, Paediat Intens Care Unit, Sydney, NSW, Australia

[10] Royal Prince Alfred Hosp, Dept Surg, Sydney, NSW, Australia

[11] Macquarie Univ, Fac Med & Hlth Sci, Sydney, NSW, Australia

[12] Western Sydney Univ, Sch Med, Sydney, NSW, Australia

来源：

TRANSPLANT INTERNATIONAL | 2021年 / 34卷 / 01期

关键词：

en bloc transplant; infant donors; kidney transplant; organ procurement; paediatric donor; surgical complications; EN-BLOC KIDNEY; RENAL-TRANSPLANTATION; GRAFT-SURVIVAL; RISK-FACTORS; RECIPIENTS; OUTCOMES; CHILDREN; GROWTH;

D O I：

10.1111/tri.13772

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Kidneys from very small donors have the potential to significantly expand the donor pool. We describe the collective experience of transplantation using kidneys from donors aged <= 1 year in Australian and New Zealand. The ANZDATA registry was analysed on all deceased donor kidney transplants from donors aged <= 1 year. We compared recipient characteristics and outcomes between 1963-1999 and 2000-2018. From 1963 to 1999, 16 transplants were performed [9 (56%) adults, 7 (44%) children]. Death-censored graft survival was 50% and 43% at 1 and 5 years, respectively. Patient survival was 90% and 87% at 1 and 5 years, respectively. From 2000 to 2018, 26 transplants were performed [25 (96%) adults, 1 (4%) children]. Mean creatinine was 73 mu mol/l +/- 49.1 at 5 years. Death-censored graft survival was 85% at 1 and 5 years. Patient survival was 100% at 1 and 5 years. Thrombosis was the cause of graft loss in 12% of recipients in the first era from 1963 to 1999, and 8% of recipients in the second era from 2000 to 2018. We advocate the judicious use of these small paediatric grafts from donors <= 1 year old. Optimal selection of donor and recipients may lead to greater acceptance and success of transplantation from very young donors.

引用

页码：118 / 126

页数：9

共 32 条

[1] Pediatric en bloc kidney transplantation into pediatric recipients: The French experience [J].