Psoriasis and bacterial superantigens - Formal or causal correlation?

被引：26
作者：
Boehncke, WH
机构：
[1] Dept. of Dermatology, Frankfurt Univ. School of Medicine, D-60590 Frankfurt
来源：
TRENDS IN MICROBIOLOGY | 1996年 / 4卷 / 12期
关键词：
D O I：
10.1016/S0966-842X(97)82910-1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Superantigens have recently been identified as candidates for triggering crucial events in the development of psoriasis. Seemingly contradictory observations may complement each other when discussed in the context of the concept of an effector cell cascade initiated by bacterial superantigens that eventually brings about disruption of peripheral tolerance of a CD8(+) T-cell subset.
引用
收藏
页码：485 / 489
页数：5
相关论文
共 38 条
  • [1] Acha-Orbea Hans, 1995, P224
  • [2] SPECIFIC NUCLEOTIDE-SEQUENCE OF HLA-C IS STRONGLY ASSOCIATED WITH PSORIASIS-VULGARIS
    ASAHINA, A
    AKAZAKI, S
    NAKAGAWA, H
    KUWATA, S
    TOKUNAGA, K
    ISHIBASHI, Y
    JUJI, T
    [J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1991, 97 (02) : 254 - 258
  • [3] AVERY AC, 1994, J IMMUNOL, V153, P4853
  • [4] GROUP-A STREPTOCOCCAL ANTIGEN-SPECIFIC-T LYMPHOCYTES IN GUTTATE PSORIATIC LESIONS
    BAKER, BS
    BOKTH, S
    POWLES, A
    GARIOCH, JJ
    LEWIS, H
    VALDIMARSSON, H
    FRY, L
    [J]. BRITISH JOURNAL OF DERMATOLOGY, 1993, 128 (05) : 493 - 499
  • [5] Pulling the trigger on psoriasis
    Boehncke, WH
    Dressel, D
    Zollner, TM
    Kaufmann, R
    [J]. NATURE, 1996, 379 (6568) : 777 - 777
  • [6] PSORIASIFORM ARCHITECTURE OF MURINE EPIDERMIS OVERLYING HUMAN PSORIATIC DERMIS TRANSPLANTED ONTO SCID MICE
    BOEHNCKE, WH
    STERRY, W
    HAINZL, A
    SCHEFFOLD, W
    KAUFMANN, R
    [J]. ARCHIVES OF DERMATOLOGICAL RESEARCH, 1994, 286 (06) : 325 - 330
  • [7] T-CELL-RECEPTOR REPERTOIRE IN CHRONIC PLAQUE-STAGE PSORIASIS IS RESTRICTED AND LACKS ENRICHMENT OF SUPERANTIGEN-ASSOCIATED V-BETA REGIONS
    BOEHNCKE, WH
    DRESSEL, D
    MANFRAS, B
    ZOLLNER, TM
    WETTSTEIN, A
    BOHM, BO
    STERRY, W
    [J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1995, 104 (05) : 725 - 728
  • [8] INDUCTION OF RELAPSING PARALYSIS IN EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS BY BACTERIAL SUPERANTIGEN
    BROCKE, S
    GAUR, A
    PIERCY, C
    GAUTAM, A
    GIJBELS, K
    FATHMAN, CG
    STEINMAN, L
    [J]. NATURE, 1993, 365 (6447) : 642 - 644
  • [9] CD8+ T-CELLS IN PSORIATIC LESIONS PREFERENTIALLY USE T-CELL RECEPTOR V(BETA)3 AND/OR V(BETA)13.1 GENES
    CHANG, JCC
    SMITH, LR
    FRONING, KJ
    SCHWABE, BJ
    LAXER, JA
    CARALLI, LL
    KURLAND, HH
    KARASEK, MA
    WILKINSON, DI
    CARLO, DJ
    BROSTOFF, SW
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (20) : 9282 - 9286
  • [10] AUTOIMMUNITY, MICROBIAL IMMUNITY AND THE IMMUNOLOGICAL HOMUNCULUS
    COHEN, IR
    YOUNG, DB
    [J]. IMMUNOLOGY TODAY, 1991, 12 (04): : 105 - 110
1234