Tamoxifen in the adjuvant setting for breast cancer: Reflexions about the risk of uterine carcinosarcoma

被引：4

作者：

Leung, F. ^{[1
]}

Terzibachian, J. -J. ^{[2
]}

Govyadovskiy, A. ^{[2
]}

Bourtembourg, A. ^{[1
]}

Maillet, R. ^{[1
]}

Riethmuller, D. ^{[1
]}

机构：

[1] CHU Besancon, Hop St Jacques, Serv Gynecol Obstet, F-25030 Besancon, France

[2] Ctr Hosp Belfort Montbeliard, Serv Gynecol Obstet, F-90016 Belfort, France

来源：

GYNECOLOGIE OBSTETRIQUE & FERTILITE | 2009年 / 37卷 / 05期

关键词：

Breast cancer; Tamoxifen; Aromatase inhibitors; Uterine carcinosarcoma; MIXED MULLERIAN TUMORS; ENDOMETRIAL CANCER; METAPLASTIC CARCINOMAS; POSTMENOPAUSAL WOMEN; RANDOMIZED-TRIALS; STAGE-I; THERAPY; SARCOMAS; ANASTROZOLE; IRRADIATION;

D O I：

10.1016/j.gyobfe.2009.03.010

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

A descriptive analysis of available data on reported cases of uterine carcinosarcomas associated with tamoxifen therapy is undertaken. The role of aromatase inhibitors as alternative to tamoxifen therapy in the adjuvant setting of breast cancer is discussed. The eventual implications of the presumed association of uterine carcinosarcoma and tamoxifen therapy on the choice of the therapeutic agent in the adjuvant setting of hormone-sensitive breast cancer are discussed. (C) 2009 Elsevier Masson SAS. All rights reserved.

引用

页码：447 / 451

页数：5

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