RETRACTED: Fabrication and mechanical characterization of a polyvinyl alcohol sponge for tissue engineering applications (Retracted Article)

被引:37
作者
Karimi, A. [1 ,2 ]
Navidbakhsh, M. [2 ]
Faghihi, S. [1 ]
机构
[1] Natl Inst Genet Engn & Biotechnol, Tissue Engn & Biomat Div, Tehran 14965161, Iran
[2] Iran Univ Sci & Technol, Dept Mech Engn, Tehran, Iran
来源
PERFUSION-UK | 2014年 / 29卷 / 03期
关键词
PVA sponge; mechanical properties; stress-strain diagram; swelling rate; tissue engineering; PVA HYDROGEL; IN-VITRO; HEALTHY; PORCINE; VIVO;
D O I
10.1177/0267659113513823
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Polyvinyl alcohol (PVA) sponges are widely used for clinical applications, including ophthalmic surgical treatments, wound healing and tissue engineering. There is, however, a lack of sufficient data on the mechanical properties of PVA sponges. In this study, a biomechanical method is used to characterize the elastic modulus, maximum stress and strain as well as the swelling ratio of a fabricated PVA sponge (P-sponge) and it is compared with two commercially available PVA sponges (CENEFOM and EYETEC). The results indicate that the elastic modulus of the P-sponge is 5.32% and 13.45% lower than that of the CENEFOM and EYETEC sponges, while it bears 4.11% more and 10.37% less stress compared to the CENEFOM and EYETEC sponges, respectively. The P-sponge shows a maximum strain of 32% more than the EYETEC sponge as well as a 26.78% higher swelling ratio, which is a significantly higher absorbency compared to the CENEFOM. It is believed that the results of this study would help for a better understanding of the extension, rupture and swelling mechanism of PVA sponges, which could lead to crucial improvement in the design and application of PVA-based materials in ophthalmic and plastic surgeries as well as wound healing and tissue engineering.
引用
收藏
页码:231 / 237
页数:7
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