Sentinel lymph node biopsy identifies occult nodal metastases in patients with Marjolin's ulcer

被引:41
作者
Eastman, AL
Erdman, WA
Lindberg, GM
Hunt, JL
Purdue, GF
Fleming, JB
机构
[1] Univ Texas, SW Med Ctr, Dept Surg, Parkland Mem Hosp, Dallas, TX 75235 USA
[2] Univ Texas, SW Med Ctr, Dept Radiol, Parkland Mem Hosp, Dallas, TX 75235 USA
[3] Univ Texas, SW Med Ctr, Dept Pathol, Parkland Mem Hosp, Dallas, TX 75235 USA
来源
JOURNAL OF BURN CARE & REHABILITATION | 2004年 / 25卷 / 03期
关键词
D O I
10.1097/01.BCR.0000124791.17426.58
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Since Marjolin's description, the management of burn scar carcinoma has remained controversial. A multitude of options and recommendations exist for the management of both primary lesions and regional nodal metastasis. This work reviews six cases of Marjolin's ulcer staged using sentinel lymph node biopsy. All primary lesions were confirmed to be squamous cell carcinoma and occurred a median of 29.5 years after burn. No patient had clinically detectable lymphadenopathy. In all cases, preoperative lymphoscintigraphy successfully identified a single draining regional nodal basin. Subsequent intraoperative lymphatic mapping/sentinel lymph node (SLN) biopsy was successful in five of six cases (83%). A successful intraoperative lymphatic mapping/SLN biopsy was defined as the identification of blue (uptake of isosulfan blue dye) or "hot" (uptake of radiolabeled sulfur colloid as measured with a handheld gamma counter) node(s) and subsequent excision. Four of five SLN biopsies identified previously occult nodal metastasis. SLN biopsy represents a minimally invasive and accurate staging procedure for Marjolin's ulcer.
引用
收藏
页码:241 / 245
页数:5
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