Protein recognition by a surface imprinted colloidal array

被引：42

作者：

Chen, Wei ^{[1
]}

Lei, Wen ^{[2
]}

Xue, Min ^{[1
]}

Xue, Fei ^{[1
]}

Meng, Zi-hui ^{[1
]}

Zhang, Wei-bing ^{[2
]}

Qu, Feng ^{[3
]}

Shea, Kenneth J. ^{[4
]}

机构：

[1] Beijing Inst Technol, Sch Chem Engn & Environm, Beijing 100081, Peoples R China

[2] E China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China

[3] Beijing Inst Technol, Sch Life Sci, Beijing 100081, Peoples R China

[4] Univ Calif Irvine, Dept Chem, Irvine, CA 92697 USA

来源：

JOURNAL OF MATERIALS CHEMISTRY A | 2014年 / 2卷 / 20期

基金：

美国国家科学基金会;

关键词：

PHOTONIC CRYSTAL SENSOR; POLYMERS; SILICA; ASSAY;

D O I：

10.1039/c4ta00048j

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A label-free and easy-to-prepare biosensor for the fast and naked-eye detection of proteins was developed in this study. A closely packed crystalline array was self-assembled in ethanol-water (1 : 1, v/v) from the surface imprinted silica (SIS) colloid for hemoglobin bovine (Hb). The reflection of the molecular imprinted colloidal array (MICA) red shifted by 23 nm in response to 1.0 mg mL(-1) of Hb at pH 7.0. Compared with the non-imprinted colloidal array (NICA), MICA has a higher selectivity towards the target protein, and can recognize the target protein via an "induced-fit" mechanism.

引用

页码：7165 / 7169

页数：5

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