Development of a Practical Method for Using Ozone Gas as a Virus Decontaminating Agent

被引:102
作者
Hudson, James B. [1 ]
Sharma, Manju [1 ]
Vimalanathan, Selvarani [1 ]
机构
[1] Viroforce Syst Inc, Lab, Vancouver, BC, Canada
关键词
Ozone; Antiviral; Decontamination; Viruses; Humidity; Ozone Generator; Catalytic Converter; Field Trials; HEALTH-CARE; DISINFECTION; INACTIVATION; EXPOSURE; ENTEROVIRUS-71; RESISTANCE; INFECTION; NOROVIRUS; INDUSTRY; FOOD;
D O I
10.1080/01919510902747969
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Our objective was to develop a practical method of utilizing the known anti-viral properties of ozone in a mobile apparatus that could be used to decontaminate rooms in health care facilities, hotels and other buildings. Maximum anti-viral efficacy required a short period of high humidity (>90% relative humidity) after the attainment of peak ozone gas concentration (20-25 ppm). All 12 viruses tested, on different hard and porous surfaces, and in the presence of biological fluids, could be inactivated by at least 3 log(10), in the laboratory and in simulated field trials. The ozone was subsequently removed by a built-in catalytic converter.
引用
收藏
页码:216 / 223
页数:8
相关论文
共 27 条
[1]   Effects of cleaning and disinfection in reducing the spread of Norovirus contamination via environmental surfaces [J].
Barker, J ;
Vipond, IB ;
Bloomfield, SF .
JOURNAL OF HOSPITAL INFECTION, 2004, 58 (01) :42-49
[3]   Ozone in the laundry industry - Practical experiences in the United Kingdom [J].
Cardis, Dick ;
Tapp, Cameron ;
DeBrum, Marc ;
Rice, Rip G. .
OZONE-SCIENCE & ENGINEERING, 2007, 29 (02) :85-99
[4]   OZONE INACTIVATES HIV AT NONCYTOTOXIC CONCENTRATIONS [J].
CARPENDALE, MTF ;
FREEBERG, JK .
ANTIVIRAL RESEARCH, 1991, 16 (03) :281-292
[5]   Ozone degradation of biological macromolecules: Proteins, hemoglobin, RNA, and DNA [J].
Cataldo, Franco .
OZONE-SCIENCE & ENGINEERING, 2006, 28 (05) :317-328
[6]   Air pollution and respiratory viral infection [J].
Ciencewicki, Jonathan ;
Jaspers, Ilona .
INHALATION TOXICOLOGY, 2007, 19 (14) :1135-1146
[7]   Evaluation of the risk of infection through exposure to aerosols and spatters in dentistry [J].
Cristina, Maria Luisa ;
Spagnolo, Anna Maria ;
Sartini, Marina ;
Dallera, Maurizio ;
Ottria, Gianluca ;
Lombardi, Roberto ;
Perdelli, Fernanda .
AMERICAN JOURNAL OF INFECTION CONTROL, 2008, 36 (04) :304-307
[8]   Time-dependent changes of inflammatory mediators in the lungs of humans exposed to 0.4 ppm ozone for 2 hr: A comparison of mediators found in bronchoalveolar lavage fluid 1 and 18 hr after exposure [J].
Devlin, RB ;
McDonnell, WF ;
Becker, S ;
Madden, MC ;
McGee, MP ;
Perez, R ;
Hatch, G ;
House, DE ;
Koren, HS .
TOXICOLOGY AND APPLIED PHARMACOLOGY, 1996, 138 (01) :176-185
[9]   Inactivation of Norovirus by ozone gas in conditions relevant to healthcare [J].
Hudson, J. B. ;
Sharma, M. ;
Petric, M. .
JOURNAL OF HOSPITAL INFECTION, 2007, 66 (01) :40-45
[10]   Effect of aqueous ozone on the NF-κB system [J].
Huth, K. C. ;
Saugel, B. ;
Jakob, F. M. ;
Cappello, C. ;
Quirling, M. ;
Paschos, E. ;
Ern, K. ;
Hickel, R. ;
Brand, K. .
JOURNAL OF DENTAL RESEARCH, 2007, 86 (05) :451-456