Debugging the intestinal microbiota in IBD

被引：4

作者：

Dessein, R. ^{[2
,3
]}

Rosenstiel, P. ^{[4
]}

Chamaillard, M. ^{[1
]}

机构：

[1] INSERM, U795, F-59037 Lille, France

[2] INSERM, U801, F-59019 Lille, France

[3] Univ Lille 2, F-59000 Lille, France

[4] Univ Hosp Schleswig Holstein, Inst Clin Mol Biol, Kiel, Germany

来源：

GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE | 2009年 / 33卷

关键词：

INFLAMMATORY-BOWEL-DISEASE; GENOME-WIDE ASSOCIATION; AVIUM SUBSP PARATUBERCULOSIS; PLACEBO-CONTROLLED TRIAL; CROHNS-DISEASE; MYCOBACTERIUM-PARATUBERCULOSIS; DOUBLE-BLIND; ULCERATIVE-COLITIS; ANTIBIOTIC-THERAPY; ILEAL MUCOSA;

D O I：

10.1016/S0399-8320(09)73148-3

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Besides its role in repelling enteropathogenic infections, the gastrointestinal tract is in intimate contact with commensal microbiota. Tremendous advances have been made in determining the pivotal role of the microbiota, in both tissue homeostasis and metabolism, as well as in the initiation and maintenance of inflammatory lesions in inflammatory bowel diseases. A better understanding of human gut microbiota could provide innovative targets for treating and/or curing such common immunopathologies of the gastrointestinal tract. (C) 2009 Elsevier Masson SAS. All rights reserved.

引用

页码：S131 / S136

页数：6

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