The myocardial and coronary histopathology and pathogenesis of hypoplastic left heart syndrome

被引：12

作者：

Cole, Charles R. ^{[1
]}

Eghtesady, Pirooz ^{[2
]}

机构：

[1] Univ Cincinnati, Cincinnati, OH USA

[2] Washington Univ, St Louis, MO 63110 USA

来源：

CARDIOLOGY IN THE YOUNG | 2016年 / 26卷 / 01期

关键词：

Hypoplastic left heart syndrome; endocardial fibroelastosis; coronary arteries; myocardial morphology; CHD; RIGHT PULMONARY-ARTERY; BICUSPID AORTIC-VALVE; ENDOCARDIAL FIBROELASTOSIS; LEFT-VENTRICLE; ANOMALOUS ORIGIN; VENTRICULOCORONARY CONNECTIONS; PRENATAL-DIAGNOSIS; NORWOOD-PROCEDURE; FIBER DISARRAY; STENOSIS;

D O I：

10.1017/S1047951115001171

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hypoplastic left heart syndrome has the greatest mortality rate among all CHDs and without palliation is uniformly fatal. Despite noble efforts, the aetiology of this syndrome is unknown and a cure remains elusive. The genetic and anatomic heterogeneity of hypoplastic left heart syndrome supports a rethinking of old hypotheses and warrants further investigation into the histological and vascular variations recognised with this syndrome. In an effort to elucidate the pathogenesis of hypoplastic left heart syndrome, this review will focus on its unique myocardial and coronary pathology as well as evaluate the association of hypoplastic left heart syndrome with the endocardial fibroelastosis reaction.

引用

页码：19 / 29

页数：11

共 67 条

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