The Number of Removed Lymph Nodes for an Acceptable False Negative Rate in Sentinel Lymph Node Biopsy for Breast Cancer

被引:5
作者
Koo, Bon Young [1 ]
Jeong, Seong Gu [1 ]
Eom, Tae Ik [1 ]
Kang, Hee Joon [1 ]
Kim, Lee Su [1 ]
机构
[1] Hallym Univ, Coll Med, Div Breast & Endocrine Surg, Anyang, South Korea
关键词
Breast cancer; False negative rate; Sentinel lymph node; POLYMERASE-CHAIN-REACTION; SUBAREOLAR INJECTION; AXILLARY DISSECTION; PLEASE STAND; MICROMETASTASES; CARCINOMA; ISOTOPE; ENOUGH; WILL;
D O I
10.4048/jbc.2009.12.2.100
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose: This study was performed to find the adequate number of removed lymph nodes to achieve an acceptable false-negative rate when performing sentinel lymph node biopsy for breast cancer. Methods: A total of 179 sentinel node biopsies combined with conventional axillary lymph node dissection for breast cancer were performed between November 2003 and June 2007. Results: The overall identification rate of sentinel lymph node and the false negative rate of the biopsy were 95.0% and 8.1%, respectively. Yet the false negative rate of the biopsy was lowered as the number of the removed nodes was increased. Especially, the false negative rate was 0% when more than 4 lymph nodes were removed. Conclusion: We recommend that four lymph nodes should be removed to obtain accurate results in sentinel node biopsy for breast cancer.
引用
收藏
页码:100 / 105
页数:6
相关论文
共 31 条
  • [1] Subareolar and peritumoral injection identify similar sentinel nodes for breast cancer
    Todd W. Bauer
    Francis R. Spitz
    Linda S. Callans
    Abass Alavi
    Rosemarie Mick
    Susan P. Weinstein
    Isabelle Bedrosian
    Douglas L. Fraker
    Thomas L. Bauer
    Brian J. Czerniecki
    [J]. Annals of Surgical Oncology, 2002, 9 (2) : 169 - 176
  • [2] Sentinel node detection and definition may depend on the imaging agent and timing
    Boxen, I
    McCready, D
    Ballinger, JR
    [J]. CLINICAL NUCLEAR MEDICINE, 1999, 24 (06) : 390 - 394
  • [3] Complementarity of blue dye and isotope in sentinel node localization for breast cancer: Univariate and multivariate analysis of 966 procedures
    Cody, HS
    Fey, J
    Akhurst, T
    Fazzari, M
    Mazumdar, M
    Yeung, H
    Yeh, SDJ
    Borgen, PI
    [J]. ANNALS OF SURGICAL ONCOLOGY, 2001, 8 (01) : 13 - 19
  • [4] Novel techniques in sentinel lymph node mapping and localization of nonpalpable breast lesions: The Moffitt experience
    Cox, CE
    Furman, B
    Dupont, EL
    Jakub, JW
    Stowell, N
    Clark, J
    Ebert, M
    [J]. ANNALS OF SURGICAL ONCOLOGY, 2004, 11 (03) : 222S - 226S
  • [5] PROGNOSTIC-SIGNIFICANCE OF BREAST-CANCER AXILLARY LYMPH-NODE MICROMETASTASES ASSESSED BY 2 SPECIAL TECHNIQUES - REEVALUATION WITH LONGER FOLLOW-UP
    DEMASCAREL, I
    BONICHON, F
    COINDRE, JM
    TROJANI, M
    [J]. BRITISH JOURNAL OF CANCER, 1992, 66 (03) : 523 - 527
  • [6] Eight false negative sentinel node procedures in breast cancer: what went wrong?
    Estourgie, SH
    Nieweg, OE
    Olmos, RAV
    Rutgers, EJT
    Peterse, JL
    Kroon, BBR
    [J]. EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 2003, 29 (04): : 336 - 340
  • [7] FISHER B, 1970, SURG GYNECOL OBSTETR, V131, P79
  • [8] A prospective study of the value of axillary node sampling in addition to sentinel lymph node biopsy in patients with breast cancer
    Hoar, FJ
    Stonelake, PS
    [J]. EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 2003, 29 (06): : 526 - 531
  • [9] Hoon DSB, 1996, INT J CANCER, V69, P369, DOI 10.1002/(SICI)1097-0215(19961021)69:5<369::AID-IJC3>3.0.CO
  • [10] 2-3