Exploiting CD22 on antigen-specific B cells to prevent allergy to the major peanut allergen Ara h 2

被引:37
|
作者
Orgel, Kelly A. [1 ,2 ,3 ]
Duan, Shiteng [4 ,5 ,6 ]
Wright, Benjamin L. [1 ,2 ,7 ]
Maleki, Soheila J. [8 ]
Wolf, John C. [8 ]
Vickery, Brian P. [1 ,2 ]
Burks, A. Wesley [1 ,2 ]
Paulson, James C. [4 ,5 ,6 ]
Kulis, Mike D. [1 ,2 ]
Macauley, Matthew S. [5 ]
机构
[1] Univ N Carolina, Sch Med, Dept Pediat, Chapel Hill, NC 27514 USA
[2] Univ N Carolina, UNC Food Allergy Initiat, Chapel Hill, NC 27514 USA
[3] Univ N Carolina, Dept Cell Biol & Physiol, Chapel Hill, NC USA
[4] Scripps Res Inst, Dept Cell & Mol Biol, La Jolla, CA 92037 USA
[5] Scripps Res Inst, Dept Physiol Chem, La Jolla, CA 92037 USA
[6] Scripps Res Inst, Dept Immunol & Microbial Sci, La Jolla, CA 92037 USA
[7] Duke Univ, Med Ctr, Dept Pediat, Durham, NC 27710 USA
[8] ARS, USDA, Southern Reg Res Ctr, New Orleans, LA USA
基金
美国国家卫生研究院;
关键词
CROSS-REACTIVITY; IGE; IMMUNOTHERAPY;
D O I
10.1016/j.jaci.2016.06.053
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
[No abstract available]
引用
收藏
页码:366 / +
页数:6
相关论文
共 50 条
  • [41] Specific ige ara h2 as an improved diagnostic marker of peanut allergy in children
    Hingley, S.
    Noimark, L.
    CLINICAL AND EXPERIMENTAL ALLERGY, 2012, 42 (12): : 1852 - 1852
  • [42] CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling
    Tedder, TF
    Tuscano, J
    Sato, S
    Kehrl, JH
    ANNUAL REVIEW OF IMMUNOLOGY, 1997, 15 : 481 - 504
  • [43] The predictive relationship between peanut- and Ara h 2-specific serum IgE concentrations and peanut allergy
    Ebisawa, Motohiro
    Moverare, Robert
    Sato, Sakura
    Borres, Magnus P.
    Ito, Komei
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2015, 3 (01): : 131 - +
  • [44] The Major Peanut Allergen Ara h 2 Produced in Nicotiana benthamiana Contains Hydroxyprolines and Is a Viable Alternative to the E. Coli Product in Allergy Diagnosis
    Uzulmez, Oyku
    Kalic, Tanja
    Mayr, Vanessa
    Lengger, Nina
    Tscheppe, Angelika
    Radauer, Christian
    Hafner, Christine
    Hemmer, Wolfgang
    Breiteneder, Heimo
    FRONTIERS IN PLANT SCIENCE, 2021, 12
  • [45] Modulation of T and B cell Responses by Virus-like particle (VLP) Expressing Peanut Allergen Ara h 2: A Novel Vaccine Candidate for Peanut Allergy
    Layhadi, Janice
    Palmer, Elizabeth
    Drazdauskaite, Gabija
    Filipaviciute, Paulina
    Devine, Alistair
    Wu, Lily
    Turner, Paul
    Patel, Nandinee
    Oluwayi, Kemi
    Rusyn, Olesya
    Skinner, Murray
    Heath, Matthew
    de Kam, Pieter-Jan
    Shamji, Mohamed
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2022, 149 (02) : AB320 - AB320
  • [46] Antigen-specific targeting and elimination of EBV-transformed B cells by allergen toxins
    Stöcker, M
    Klockenbring, T
    Huhn, M
    Nachreiner, T
    Wicklein, D
    Petersen, A
    Bauer, R
    Goerlich, R
    Fischer, R
    Barth, S
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2005, 116 (04) : 910 - 915
  • [47] Homology modelling of the major peanut allergen Ara h 2 and surface mapping of IgE-binding epitopes
    Barre, A
    Borges, JP
    Culerrier, R
    Rougé, P
    IMMUNOLOGY LETTERS, 2005, 100 (02) : 153 - 158
  • [48] IgE cross-reactivity between the major peanut allergen Ara h 2 and tree nut allergens
    de Leon, M. P.
    Drew, A. C.
    Glaspole, I. N.
    Suphioglu, C.
    O'Hehir, R. E.
    Rolland, J. M.
    MOLECULAR IMMUNOLOGY, 2007, 44 (04) : 463 - 471
  • [49] Biomarkers for peanut allergy in peripheral blood derived from a whole mRNA screen in Ara h 2 specific T cells
    Saidova, A.
    Fajgelj, V
    Bublin, M.
    Schmidthaler, K.
    Klingelmueller, F.
    Szepfalusi, Z.
    Breiteneder, H.
    Eiwegger, T.
    ALLERGY, 2016, 71 : 160 - 161
  • [50] Contribution of Sequential and Conformational IgE-Binding Epitopes to the Allergenicity of Major Peanut Allergen Ara h 2
    Hazebrouck, Stephane
    Guillon, Blanche
    Drumare, Marie-Francoise
    Paty, Evelyne
    Wal, Jean-Michel
    Bernard, Herve
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 133 (02) : AB398 - AB398