Prevalence of Panton-Valentine leukocidin genes in methicillin-resistant Staphylococcus aureus isolates phenotypically consistent with community-acquired MRSA, 1999-2007, Vienna General Hospital

被引:8
作者
Bauer, C. C. [1 ]
Apfalter, P. [2 ]
Daxboeck, F. [1 ]
Bachhofner, N. [1 ]
Stadler, M. [1 ]
Blacky, A. [1 ]
Diab-Elschahawi, M. [1 ]
Assadian, O. [1 ]
机构
[1] Med Univ Vienna, Div Hosp Hyg, Clin Inst Hyg & Med Microbiol, A-1090 Vienna, Austria
[2] Med Univ Vienna, Div Clin Microbiol, Clin Inst Hyg & Med Microbiol, A-1090 Vienna, Austria
关键词
INFECTIONS;
D O I
10.1007/s10096-009-0721-9
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The purpose of this study was to investigate methicillin-resistant Staphylococcus aureus (MRSA) isolates with antibiotic resistance restricted to beta-lactam antibiotics and variable resistance to fusidic acid for the presence of Panton-Valentine leukocidin (PVL) genes. Our data show that the selected resistance pattern is found rarely among MRSA isolates in our hospital, but it appears that this phenotype consistent with typical community-acquired (ca) MRSA is indicative of PVL-positive MRSA.
引用
收藏
页码:909 / 912
页数:4
相关论文
共 14 条
[1]   Community-acquired methicillin-resistant Staphylococcus aureus:: the role of Panton-Valentine Leukocidin [J].
Boyle-Vavra, Susan ;
Daum, Robert S. .
LABORATORY INVESTIGATION, 2007, 87 (01) :3-9
[2]  
Chizzali-Bonfadin C, 1995, Medinfo, V8 Pt 2, P1684
[3]   The molecular evolution of methicillin-resistant Staphylococcus aureus [J].
Deurenberg, R. H. ;
Vink, C. ;
Kalenic, S. ;
Friedrich, A. W. ;
Bruggeman, C. A. ;
Stobberingh, E. E. .
CLINICAL MICROBIOLOGY AND INFECTION, 2007, 13 (03) :222-235
[4]   The emergence of infections with community-associated methicillin resistant Staphylococcus aureus [J].
Diederen, BMW ;
Kluytmans, JAJW .
JOURNAL OF INFECTION, 2006, 52 (03) :157-168
[5]   Rapid and reliable detection of multiresistant Staphylococcus aureus (MRSA) using a multiplex PCR [J].
Domann, E ;
Hossain, H ;
Füssle, R ;
Chakraborty, T .
DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 2000, 125 (20) :613-618
[6]  
Friedrich AW, 2006, EUROSURVEILLANCE, V11, pE0601124
[7]   Typing of methicillin-resistant Staphylococcus aureus in a university hospital setting by using novel software for spa repeat determination and database management [J].
Harmsen, D ;
Claus, H ;
Witte, W ;
Rothgänger, J ;
Claus, H ;
Turnwald, D ;
Vogel, U .
JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (12) :5442-5448
[8]   Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia [J].
Lina, G ;
Piémont, Y ;
Godail-Gamot, F ;
Bes, M ;
Peter, MO ;
Gauduchon, V ;
Vandenesch, F ;
Etienne, J .
CLINICAL INFECTIOUS DISEASES, 1999, 29 (05) :1128-1132
[9]  
NCCLS, 1999, M100S9 NCCLS, pM100
[10]   Dissemination of new methicillin-resistant Staphylococcus aureus clones in the community [J].
Okuma, K ;
Iwakawa, K ;
Turnidge, JD ;
Grubb, WB ;
Bell, JM ;
O'Brien, FG ;
Coombs, GW ;
Pearman, JW ;
Tenover, FC ;
Kapi, M ;
Tiensasitorn, C ;
Ito, T ;
Hiramatsu, K .
JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (11) :4289-4294