Total synthesis of (±)-quadrangularin A

被引：76
作者：
Li, Wenling
Li, Hao
Li, Ying
Hou, Zijie
机构：
[1] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
[2] Lanzhou Railway Univ, Dept Biol & Chem Engn, Lanzhou 730000, Peoples R China
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 45期
关键词：
biomimetic synthesis; natural products; oligostilbenes; oxidative coupling; total synthesis;
D O I：
10.1002/anie.200603097
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The key to successful coupling in the synthesis of (±)- quadrangularin A (1) was the introduction of tert-butyl groups in the precursor to block two reactive positions. Thus, the oxidative coupling of 3,5-di-(tert-butyl) resveratrol was carried out regioselectively in an efficient total synthesis of the natural product. (Chemical Equation Presented) © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.
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收藏
页码：7609 / 7611
页数：3
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