Is There a Role for mTOR Inhibitors in Renal Transplantation?

被引:1
作者
Zaltzman, Jeffrey Steven [1 ]
机构
[1] Univ Toronto, St Michaels Hosp, Dept Med, Div Nephrol & Transplant, Toronto, ON, Canada
关键词
MAINTENANCE IMMUNOSUPPRESSION; KIDNEY-TRANSPLANTATION; RAPAMYCIN INHIBITORS; RECIPIENTS; EFFICACY; TARGET;
D O I
10.1097/TP.0000000000001541
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:228 / 229
页数:2
相关论文
共 10 条
  • [1] Five-Year Outcomes in Kidney Transplant Patients Converted From Cyclosporine to Everolimus: The Randomized ZEUS Study
    Budde, K.
    Lehner, F.
    Sommerer, C.
    Reinke, P.
    Arns, W.
    Eisenberger, U.
    Wuethrich, R. P.
    Muehlfeld, A.
    Heller, K.
    Porstner, M.
    Veit, J.
    Paulus, E. -M.
    Witzke, O.
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2015, 15 (01) : 119 - 128
  • [2] KIDNEY
    Hart, A.
    Smith, J. M.
    Skeans, M. A.
    Gustafson, S. K.
    Stewart, D. E.
    Cherikh, W. S.
    Wainright, J. L.
    Boyle, G.
    Snyder, J. J.
    Kasiske, B. L.
    Israni, A. K.
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2016, 16 : 11 - 46
  • [3] Clinical efficacy of mTOR inhibitors in solid tumors: a systematic review
    Huang, Zebo
    Wu, Yinxia
    Zhou, Xin
    Qian, Jiaqi
    Zhu, Wei
    Shu, Yongqian
    Liu, Ping
    [J]. FUTURE ONCOLOGY, 2015, 11 (11) : 1687 - 1699
  • [4] Inhibitors of mTOR and Risks of Allograft Failure and Mortality in Kidney Transplantation
    Isakova, T.
    Xie, H.
    Messinger, S.
    Cortazar, F.
    Scialla, J. J.
    Guerra, G.
    Contreras, G.
    Roth, D.
    Burke, G. W., III
    Molnar, M. Z.
    Mucsi, I.
    Wolf, M.
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2013, 13 (01) : 100 - 110
  • [5] Maintenance immunosuppression with target-of-rapamycin inhibitors is associated with a reduced incidence of de novo malignancies
    Kauffman, HM
    Cherikh, WS
    Cheng, YL
    Hanto, DW
    Kahan, BD
    [J]. TRANSPLANTATION, 2005, 80 (07) : 883 - 889
  • [6] Effect of sirolimus on malignancy and survival after kidney transplantation: systematic review and meta-analysis of individual patient data
    Knoll, Greg A.
    Koko, Madzouka B.
    Lick, Ranjeeta Ma
    Beck, Andrew
    Buenaventura, Chieny D.
    Ducharme, Robin
    Barsoum, Rashad
    Bernasconi, Corrado
    Blydt-Hansen, Tom D.
    Ekberg, Henrik
    Felipe, Claudia R.
    Firth, John
    Gallon, Lorenzo
    Gelens, Marielle
    Glotz, Denis
    Gossmann, Jan
    Guba, Markus
    Morsy, Ahmed Ali
    Salgo, Rebekka
    Scheuermann, Earnst H.
    Tedesco-Silva, Helio
    Vitko, Stefan
    Watson, Christopher
    Fergusson, Dean A.
    [J]. BMJ-BRITISH MEDICAL JOURNAL, 2014, 349
  • [7] A Systematic Review of Conversion From Calcineurin Inhibitor to Mammalian Target of Rapamycin Inhibitors for Maintenance Immunosuppression in Kidney Transplant Recipients
    Lim, W. H.
    Eris, J.
    Kanellis, J.
    Pussell, B.
    Wiid, Z.
    Witcombe, D.
    Russ, G. R.
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2014, 14 (09) : 2106 - 2119
  • [8] A worldwide, phase III, randomized, controlled, safety and efficacy study of a sirolimus/cyclosporine regimen for prevention of acute rejection in recipients of primary mismatched renal allografts
    MacDonald, AS
    [J]. TRANSPLANTATION, 2001, 71 (02) : 271 - 280
  • [9] Association of Baseline Viral Serology and Sirolimus Regimens With Kidney Transplant Outcomes: A 14-Year Registry-Based Cohort Study in the United States
    Santos, Alfonso H., Jr.
    Casey, Michael J.
    Wen Xuerong
    Womer, Karl L.
    [J]. TRANSPLANTATION, 2017, 101 (02) : 377 - 386
  • [10] Wiederrecht G J, 1995, Prog Cell Cycle Res, V1, P53