A novel flavanone from Ilex hainanensis Merr.

被引:24
作者
Chen, Xiao-Qing [1 ]
Zan, Ke [1 ]
Yang, Jie [1 ]
Lai, Mao-Xiang [2 ]
Wang, Qiang [1 ]
机构
[1] China Pharmaceut Univ, Key Lab Modern Chinese Med, Minist Educ, Nanjing 210009, Peoples R China
[2] Guangxi Acad Chinese Med & Pharmaceut Sci, Guangxi 530022, Peoples R China
关键词
Ilex hainanensis Merr; Huazhongilexone-7-O--D-glucopyranoside; antioxidant activity; CONFIGURATION; DERIVATIVES; GLYCOSIDES;
D O I
10.1080/14786410802044885
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Chemical investigation of the leaves of Ilex hainanensis Merr. yielded a new flavanone named Huazhongilexone-7-O--D-glucopyranoside, together with five known compounds, which included caffeic acid, quercetin, isoquercitrin, quercitrin-7-O--D-glucopyranoside and rutin. All of the compounds were isolated from the plant for the first time. The structure of the new compound was determined on the basis of high resolution mass, 1D and 2D NMR spectroscopies including ROESY. The antioxidant activity of the new compound was assessed using the DPPH spectrophotometric and IC50 value was 10.39 mol L-1.
引用
收藏
页码:442 / 447
页数:6
相关论文
共 10 条
[1]  
Chen Y. X., 2004, TRADITIONAL CHINESE, V7, P4
[2]  
CLARKLEWIS JW, 1968, AUST J CHEM, V21, P2059
[4]  
JOHN AHS, 2006, NATURAL PRODUCT RES, V20, P1046
[5]  
Lin Li-Dong, 1994, Acta Botanica Sinica, V36, P393
[6]   C-13 NMR-STUDIES OF FLAVONOIDS .3. NATURALLY OCCURRING FLAVONOID GLYCOSIDES AND THEIR ACYLATED DERIVATIVES [J].
MARKHAM, KR ;
TERNAI, B ;
STANLEY, R ;
GEIGER, H ;
MABRY, TJ .
TETRAHEDRON, 1978, 34 (09) :1389-1397
[7]   Metabolism of rosmarinic acid in rats [J].
Nakazawa, T ;
Ohsawa, K .
JOURNAL OF NATURAL PRODUCTS, 1998, 61 (08) :993-996
[9]   Triterpenoids from the leaves of Ilex hainanensis [J].
Zhou, Si-Xiang ;
Yang, Jun-Shan ;
Liu, Fu-Cheng ;
Tu, Peng-Fei .
HELVETICA CHIMICA ACTA, 2007, 90 (01) :121-127
[10]   Complete assignments of 1H and 13C NMR spectroscopic data for two new triterpenoid saponins from Ilex hainanensis [J].
Zhou, Sixiang ;
Yang, Junshan ;
Liu, Fucheng ;
Tu, Pengfei .
MAGNETIC RESONANCE IN CHEMISTRY, 2007, 45 (02) :179-181