Mass spectrometry: Bottom-up or top-down?

被引:308
作者
Chait, Brian T. [1 ]
机构
[1] Rockefeller Univ, Lab Mass Spectrometry & Gaseous Ion Chem, New York, NY 10021 USA
关键词
D O I
10.1126/science.1133987
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
A novel approach to mass spectrometry involving fragmentation of intact proteins in the gas phase promises to greatly improve our ability to determine protein modifications.
引用
收藏
页码:65 / 66
页数:2
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