Malignant solitary fibrous tumor of the thyroid: a case-report and review of the literature

被引：11

作者：

Alves Filho, Wellington ^{[1
]}

da Graca Lorencetti Mahmoud, Renata Regina ^{[1
]}

Ramos, Daniel Marin ^{[1
]}

Furtado de Araujo-Filho, Vergilius Jose ^{[1
]}

de Lima, Patricia Picciarelli ^{[2
]}

Cernea, Claudio Roberto ^{[1
]}

Brandao, Lenine Garcia ^{[1
]}

机构：

[1] Univ Sao Paulo, Dept Head & Neck Surg, Sch Med, FMUSP, Sao Paulo, Brazil

[2] FMUSP, Dept Pathol, Sao Paulo, Brazil

来源：

ARQUIVOS BRASILEIROS DE ENDOCRINOLOGIA E METABOLOGIA | 2014年 / 58卷 / 04期

关键词：

GLAND;

D O I：

10.1590/0004-2730000003230

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Solitary fibrous tumor (SFT) is an uncommon spindle-cell neoplasm that most often involves the pleura, rarely occurring in extra-thoracic locations. Twenty-six cases of SFT arising in the thyroid gland have been described. We report a case of a 60-year-old woman presenting an 8-month history of enlargement of the neck associated with dysphagia. The patient underwent a right hemithyroidectomy and SFT of the thyroid was diagnosed. Immunohistochemistry showed positivity for CD34 marker, and the high number of mitoses and the presence of cellular atypia suggested that the tumor was malignant. To our knowledge, this is the second case of malignant SFT of the thyroid gland ever reported. Due to the rarity of these tumors, the indication of adjuvant therapy and prognosis are uncertain. Long-term follow-up after surgical resection seems to be advisable.

引用

页码：402 / 406

页数：5

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