Semantic and pharmacological aspects towards a new classification of antipsychotic drugs

被引:0
作者
Costentin, J. [1 ]
机构
[1] Fac Med & Pharm, CNRS, Unite Neuropsychopharmacol, F-76183 Rouen, France
来源
PSN-PSYCHIATRIE SCIENCES HUMAINES NEUROSCIENCES | 2009年 / 7卷 / 01期
关键词
Antipsychotic drugs; Neuroleptic drugs; Extrapyramidal side effects; Antideficit effects; Antagonists of cholinergic muscarinic receptors; DOPAMINE-RECEPTORS; AGONISTS; OCCUPANCY; D-2;
D O I
10.1007/s11836-009-0080-8
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The main stages involved in the development of drugs effective against psychotic manifestations are presented, as well as their mechanisms of action. Justification is given for the terms antipsychotic drugs, neuroleptic antipsychotic drugs, non-neuroleptic antipsychotic drugs, and non neuroleptic antipsychotic drugs, effective against negative expressions of schizophrenia. These constitute the basis of the new classification of antipsychotic drugs suggested. Finally, the term "atypical neuroleptic drugs", frequently used in France, is described as badly constructed and unfortunate and should therefore be abandoned.
引用
收藏
页码:31 / 34
页数:4
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