Changes in quantitative ultrasound imaging as the predictor of response to neoadjuvant chemotherapy in patients with breast cancer

被引：1

作者：

Piotrzkowska-Wroblewska, Hanna ^{[1
]}

Dobruch-Sobczak, Katarzyna ^{[2
]}

Gumowska, Magdalena ^{[2
]}

Litniewski, Jerzy ^{[1
]}

机构：

[1] Inst Fundamental Technol Res PAS, Dept Ultrasound, Warsaw, Poland

[2] Maria Sklodowska Curie Natl Res Inst Oncol, Dept Radiol, Warsaw, Poland

来源：

2022 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS) | 2022年

关键词：

breast cancer; neoadjuvant chemotherapy; ultrasound; H-scan ultrasounds;

D O I：

10.1109/IUS54386.2022.9957940

中图分类号：

O42 [声学];

学科分类号：

070206 ; 082403 ;

摘要：

The presented study demonstrates the effectiveness of quantitative ultrasound imaging (H-scan ultrasound) in monitoring the breast cancer response to neoadjuvant chemotherapy and predicting pathological response. A group of 40 patients (51 breast tumors) participated in the study. The results showed that QUS imaging was able to distinguish between breast cancer patients responding and not responding to chemotherapy early in the course of treatment. Analysis of the percentage changes in red in the parametric images showed that this parameter can predict the response to treatment of patients with the area under the receiver operational characteristics (ROC) curve of 0.61, 0.70, 0.83, and 0.86, respectively, one week after 1st, 2nd, 3rd and 4th dose of treatment.

引用

页数：4

共 8 条

[1]

Baek J., AIUM 2022

[2] Ultrasound Imaging of Apoptosis in Tumor Response: Novel Preclinical Monitoring of Photodynamic Therapy Effects [J].

Banihashemi, Behzad ;

Vlad, Roxana ;

Debejevic, Branislav ;

Giles, Anoja ;

Kolios, Michael C. ;

Czarnota, Gregory J. .

CANCER RESEARCH, 2008, 68 (20) :8590-8596

[3] Ultrasonic biomicroscopy of viable, dead and apoptotic cells [J].

Czarnota, GJ ;

Kolios, MC ;

Vaziri, H ;

Benchimol, S ;

Ottensmeyer, FP ;

Sherar, MD ;

Hunt, JW .

ULTRASOUND IN MEDICINE AND BIOLOGY, 1997, 23 (06) :961-965

[4] Cancer incidence and mortality patterns in Europe: Estimates for 40 countries and 25 major cancers in 2018 [J].

Ferlay, J. ;

Colombet, M. ;

Soerjomataram, I. ;

Dyba, T. ;

Randi, G. ;

Bettio, M. ;

Gavin, A. ;

Visser, O. ;

Bray, F. .

EUROPEAN JOURNAL OF CANCER, 2018, 103 :356-387

[5] Scattering and reflection identification in H-scan images [J].

Parker, K. J. .

PHYSICS IN MEDICINE AND BIOLOGY, 2016, 61 (12) :L20-L28

[6] Breast cancer resistance to chemotherapy: When should we suspect it and how can we prevent it? [J].

Prihantono ;

Faruk, Muhammad .

ANNALS OF MEDICINE AND SURGERY, 2021, 70

[7] Low-frequency quantitative ultrasound imaging of cell death in vivo [J].

Sadeghi-Naini, Ali ;

Papanicolau, Naum ;

Falou, Omar ;

Tadayyon, Hadi ;

Lee, Justin ;

Zubovits, Judit ;

Sadeghian, Alireza ;

Karshafian, Raffi ;

Al-Mahrouki, Azza ;

Giles, Anoja ;

Kolios, Michael C. ;

Czarnota, Gregory J. .

MEDICAL PHYSICS, 2013, 40 (08)

[8] Quantitative Ultrasound Characterization of Responses to Radiotherapy in Cancer Mouse Models [J].

Vlad, Roxana M. ;

Brand, Sebastian ;

Giles, Anoja ;

Kolios, Michael C. ;

Czarnota, Gregory J. .

CLINICAL CANCER RESEARCH, 2009, 15 (06) :2067-2075

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