Chimerism after organ transplantation

被引:23
|
作者
Starzl, TE
Demetris, AJ
Murase, N
Trucco, M
Thomson, AW
Rao, AS
Fung, JJ
机构
[1] UNIV PITTSBURGH,MED CTR,PITTSBURGH TRANSPLANT INST,PITTSBURGH,PA
[2] UNIV PITTSBURGH,MED CTR,DEPT SURG,PITTSBURGH,PA
[3] UNIV PITTSBURGH,MED CTR,DEPT PATHOL,PITTSBURGH,PA
[4] UNIV PITTSBURGH,MED CTR,DEPT PEDIAT,PITTSBURGH,PA
来源
关键词
D O I
10.1097/00041552-199705000-00015
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Recent evidence suggests that: passenger leukocytes migrate after organ transplantation and produce persistent chimerism, which is essential for sustained survival of the allograft, Here, we describe how this hematolymphopoietic chimerism provides an important framework for interpretation of post-transplant phenomena and for initiation of therapeutically oriented transplantation research.
引用
收藏
页码:292 / 298
页数:7
相关论文
共 50 条
  • [1] Chimerism after solid organ transplantation
    Mengel, M
    Lehmann, U
    Kreipe, H
    AMERICAN JOURNAL OF TRANSPLANTATION, 2005, 5 (12) : 3021 - 3021
  • [2] LYMPHOCYTE CHIMERISM AFTER ORGAN-TRANSPLANTATION
    JOYSEY, VC
    WOOD, H
    RAMSBOTTOM, S
    MORGAN, H
    FORD, C
    HORSFORD, J
    JAMIESON, N
    FRIEND, P
    ALEXANDER, G
    CALNE, RY
    TRANSPLANTATION PROCEEDINGS, 1992, 24 (06) : 2519 - 2522
  • [3] Chimerism after organ transplantation: Is there any clinical significance?
    Burlingham, WJ
    CLINICAL TRANSPLANTATION, 1996, 10 (01) : 110 - 117
  • [4] Chimerism after solid organ transplantation: Not only numbers count
    Koopmans, M
    Hovinga, ICLK
    de Heer, E
    Bruijn, JA
    Bajema, IM
    AMERICAN JOURNAL OF TRANSPLANTATION, 2005, 5 (12) : 3022 - 3022
  • [5] Immunoregulatory role of chimerism in clinical organ transplantation
    JM Mathew
    J Miller
    Bone Marrow Transplantation, 2001, 28 : 115 - 119
  • [6] Immunoregulatory role of chimerism in clinical organ transplantation
    Mathew, JM
    Miller, J
    BONE MARROW TRANSPLANTATION, 2001, 28 (02) : 115 - 119
  • [7] Chimerism in organ transplantation: Conflicting experiments and clinical observations
    Monaco, AP
    Medawar, P
    TRANSPLANTATION, 2003, 75 (09) : 13S - 16S
  • [8] CELL-MIGRATION AND CHIMERISM AFTER WHOLE-ORGAN TRANSPLANTATION - THE BASIS OF GRAFT ACCEPTANCE
    STARZL, TE
    DEMETRIS, AJ
    TRUCCO, M
    MURASE, N
    RICORDI, C
    ILDSTAD, S
    RAMOS, H
    TODO, S
    TZAKIS, A
    FUNG, JJ
    NALESNIK, M
    ZEEVI, A
    RUDERT, WA
    KOCOVA, M
    HEPATOLOGY, 1993, 17 (06) : 1127 - 1152
  • [9] MIXED CHIMERISM TO INDUCE TOLERANCE FOR SOLID ORGAN-TRANSPLANTATION
    WREN, SM
    NALESNIK, M
    HRONAKES, ML
    OH, E
    ILDSTAD, ST
    JOURNAL OF PEDIATRIC SURGERY, 1991, 26 (04) : 439 - 443
  • [10] Chimerism after paediatric stem cell transplantation
    Bilgen, H
    Aydin, F
    Ozdilli, K
    Savran, F
    Anak, S
    Ozgenc, S
    Carin, M
    Gedikoglu, G
    BONE MARROW TRANSPLANTATION, 2004, 33 : S220 - S220