Synthesis and Utility of Dihydropyridine Boronic Esters

被引：51

作者：

Panda, Santanu ^{[1
]}

Coffin, Aaron ^{[1
]}

Nhu Nguyen, Q. ^{[2
]}

Tantillo, Dean J. ^{[2
]}

Ready, Joseph M. ^{[1
]}

机构：

[1] Univ Texas SW Med Ctr Dallas, Dept Biochem, Div Chem, Dallas, TX 75390 USA

[2] Univ Calif Davis, Dept Chem, Davis, CA 95616 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2016年 / 55卷 / 06期

关键词：

allylic compounds; boron; heterocycles; samarium iodide; synthetic methods; CROSS-COUPLING REACTIONS; C-H ARYLATION; NITROGEN-HETEROCYCLES; SAMARIUM(II) IODIDE; ORGANIC-CHEMISTRY; DIRECT ALKYLATION; NATURAL-PRODUCT; ACIDS; SECONDARY; PYRIDINES;

D O I：

10.1002/anie.201510027

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

When activated by an acylating agent, pyridine boronic esters react with organometallic reagents to form a dihydropyridine boronic ester. This intermediate allows access to a number of valuable substituted pyridine, dihydropyridine, and piperidine products.

引用

页码：2205 / 2209

页数：5

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