Comparison Between Prothioconazole and Prothioconazole-Desthio in Poison-Plate Mycelial Growth Assays of Fusarium graminearum

被引:4
作者
Breunig, Mikaela [1 ]
Chilvers, Martin, I [1 ]
机构
[1] Michigan State Univ, Dept Plant Soil & Microbial Sci, E Lansing, MI 48824 USA
来源
PLANT HEALTH PROGRESS | 2022年 / 23卷 / 02期
关键词
chemical control; epidemiology; field crops; pesticide resistance; HEAD BLIGHT; SENSITIVITY; WHEAT; TEBUCONAZOLE; METCONAZOLE; FUNGICIDES;
D O I
10.1094/PHP-06-21-0087-RS
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The active ingredient prothioconazole is a demethylase inhibitor (DMI) widely used in numerous commercial fungicide formulations for crop protection. However, prothioconazole converts in planta to prothioconazole-desthio, which was found to be the primary active form inhibiting CYP51 activity in fungi. Here, experiments were performed on Fusarium graminearum to compare the use of technical-grade prothioconazole-desthio, technical-grade prothioconazole, and formulated product Proline in poison-plate mycelial growth assays to investigate the relevancy of using prothioconazole for sensitivity testing. Prothioconazole-desthio was significantly more efficacious at mycelial growth inhibition than prothioconazole but mycelial growth and effective concentration to reduce growth by 50% (EC50) values between the two correlated significantly. Although care should be taken in interpreting EC50 values of prothioconazole, the compound is still suitable for monitoring sensitivity rather than purchasing the more expensive prothioconazole-desthio.
引用
收藏
页码:159 / 161
页数:3
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