Biphenyl-based phosphine: A well-defined, air-stable, and efficient ligand for the Mizoroki-Heck reaction

被引：39

作者：

Nadri, Shirin ^{[1
]}

Joshaghani, Mohammad ^{[1
,2
]}

Rafiee, Ezzat ^{[1
,2
]}

机构：

[1] Razi Univ, Fac Chem, Kermanshah 67149, Iran

[2] Kermanshah Oil Refining Co, Kermanshah, Iran

来源：

APPLIED CATALYSIS A-GENERAL | 2009年 / 362卷 / 1-2期

关键词：

C-C coupling; Mizoroki-Heck Reaction; Biphenyl-based phosphine; Palladium catalyst; CROSS-COUPLING REACTIONS; HIGHLY-ACTIVE CATALYST; ARYL CHLORIDES; BOND FORMATION; PALLADIUM CATALYSIS; C-C; HALIDES; ARYLATION; BROMIDES; OLEFINS;

D O I：

10.1016/j.apcata.2009.04.038

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

An efficient and stereoselective catalytic system has been reported for the Mizoroki-Heck cross coupling using a moderately bulky and electron-rich biphenyl-based phosphine, P(o-C6H4C6H4Me)Ph-2 and a low Pd(OAc)(2) loading. It is found that the nature of olefin has more beneficial effect on the reaction times and yields than the aryl halide which may be due to more contribution of the coordination and/or insertion of the olefin in the rate-determining step of the Heck reaction. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：163 / 168

页数：6

共 53 条

[1] Anionic Pd(0) and Pd(II) intermediates in palladium-catalyzed Heck and cross-coupling reactions [J].