Effect of temperature on separation of purine and pyrimidine bases on novel chelating resin

被引：6

作者：

Ayar, A ^{[1
]}

Mercimek, B

Kara, H

Çengeloglu, Y

机构：

[1] Univ Nigde, Fac Arts & Sci, Dept Chem, TR-51200 Nigde, Turkey

[2] Univ Selcuk, Fac Arts & Sci, Dept Chem, Konya, Turkey

来源：

SEPARATION AND PURIFICATION TECHNOLOGY | 2002年 / 28卷 / 01期

关键词：

ligand-exchange chromatography; nucleic acid bases; nucleosides; PLH2;

D O I：

10.1016/S1383-5866(02)00005-9

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

The novel chelating resin poly-bis [4-(4'-biphenyl)oxamidine]-diaminoglyoxime (PLH2) has been modified as ligand-exchange material with Co(II). The possibility of using PLH2 as ligand exchanger in the chromatographic separation of nucleic acid bases and nucleosides has been studied at various temperatures. PLH2 offers the advantage of combining high sorption capacity with high selectivity for the ligands. It has a strong driving force for ligand sorption. Ligand-exchange chromatography on Co(II)-loaded functionalized PLH2 can be a useful alternative method for separation of nucleic acid bases and nucleosides. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：25 / 28

页数：4

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