Gastrointestinal changes after bariatric surgery

被引：96

作者：

Quercia, I. ^{[1
,4
]}

Dutia, R. ^{[1
,4
]}

Kotler, D. P. ^{[3
,4
,6
]}

Belsley, S. ^{[5
,6
]}

Laferrere, B. ^{[1
,2
,4
,6
]}

机构：

[1] Columbia Univ, Coll Phys & Surg, St Lukes Roosevelt Hosp Ctr, New York Obes Nutr Res Ctr, New York, NY 10025 USA

[2] Columbia Univ, St Lukes Roosevelt Hosp Ctr, Div Endocrinol Diabet & Nutr, New York, NY 10025 USA

[3] Columbia Univ, St Lukes Roosevelt Hosp Ctr, Div Gastroenterol & Liver Dis, New York, NY 10025 USA

[4] Columbia Univ, St Lukes Roosevelt Hosp Ctr, Dept Med, New York, NY 10025 USA

[5] Columbia Univ, St Lukes Roosevelt Hosp Ctr, Dept Surg, New York, NY 10025 USA

[6] Columbia Univ, Coll Phys & Surg, New York, NY 10025 USA

来源：

DIABETES & METABOLISM | 2014年 / 40卷 / 02期

关键词：

Obesity; Bariatric surgery; Gastric bypass; Diabetes; Gut peptides; GASTRIC BYPASS-SURGERY; PLASMA GHRELIN LEVELS; VERTICAL SLEEVE GASTRECTOMY; GLUCAGON-LIKE PEPTIDE-1; HUMAN GUT MICROBIOTA; INDUCED WEIGHT-LOSS; BODY-MASS INDEX; JEJUNOILEAL BYPASS; BILE-ACIDS; SURGICAL-TREATMENT;

D O I：

10.1016/j.diabet.2013.11.003

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Severe obesity is a preeminent health care problem that impacts overall health and survival. The most effective treatment for severe obesity is bariatric surgery, an intervention that not only maintains long-term weight loss but also is associated with improvement or remission of several comorbidies including type 2 diabetes mellitus. Some weight loss surgeries modify the gastrointestinal anatomy and physiology, including the secretions and actions of gut peptides. This review describes how bariatric surgery alters the patterns of gastrointestinal motility, nutrient digestion and absorption, gut peptide release, bile acids and the gut microflora, and how these changes alter energy homeostasis and glucose metabolism. (C) 2013 Elsevier Masson SAS. All rights reserved.

引用

页码：87 / 94

页数：8

共 101 条

[1] Plasma ghrelin concentratin in the short-term following biliopancreatic diversion [J].

Adami, GF ;

Cordera, R ;

Marinari, G ;

Lamerini, G ;

Andraghetti, G ;

Scopinaro, N .

OBESITY SURGERY, 2003, 13 (06) :889-892

[2]

Ahmad NN, 2013, INT J OBES, DOI 10.1038

[3] Gastric Emptying is not Affected by Sleeve Gastrectomy-Scintigraphic Evaluation of Gastric Emptying after Sleeve Gastrectomy without Removal of the Gastric Antrum [J].

Bernstine, Hanna ;

Tzioni-Yehoshua, Ronit ;

Groshar, David ;

Beglaibter, Nahum ;

Shikora, Scott ;

Rosenthal, Raul J. ;

Rubin, Moshe .

OBESITY SURGERY, 2009, 19 (03) :293-298

[4] Lower gastrointestinal functions [J].

Bharucha, A. E. .

NEUROGASTROENTEROLOGY AND MOTILITY, 2008, 20 :103-113

[5] PYY3-36 as an anti-obesity drug target [J].

Boggiano, MM ;

Chandler, PC ;

Oswald, KD ;

Rodgers, RJ ;

Blundell, JE ;

Ishii, Y ;

Beattie, AH ;

Holch, P ;

Allison, DB ;

Schindler, M ;

Arndt, K ;

Rudolf, K ;

Mark, M ;

Schoelch, C ;

Joost, HG ;

Klaus, S ;

Thöne-Reineke, C ;

Benoit, SC ;

Seeley, RJ ;

Beck-Sickinger, AG ;

Koglin, N ;

Raun, K ;

Madsen, K ;

Wulff, BS ;

Stidsen, CE ;

Birringer, M ;

Kreuzer, OJ ;

Deng, XY ;

Whitcomb, DC ;

Halem, H ;

Taylor, J ;

Dong, J ;

Datta, R ;

Culler, M ;

Ortmann, S ;

Castañeda, TR ;

Tschöp, M .

OBESITY REVIEWS, 2005, 6 (04) :307-322

[6] Biliopancreatic diversion in rats is associated with intestinal hypertrophy and with increased GLP-1, GLP-2 and PYY levels [J].

Borg, Cynthia M. ;

Le Roux, Carel W. ;

Ghatei, Mohammad A. ;

Bloom, Stephen R. ;

Patel, Ameet G. .

OBESITY SURGERY, 2007, 17 (09) :1193-1198

[7] Superior Appetite Hormone Profile After Equivalent Weight Loss by Gastric Bypass Compared to Gastric Banding [J].

Bose, Mousumi ;

Machineni, Sriram ;

Olivan, Blanca ;

Teixeira, Julio ;

McGinty, James J. ;

Bawa, Baani ;

Koshy, Ninan ;

Colarusso, Antonia ;

Laferrere, Blandine .

OBESITY, 2010, 18 (06) :1085-1091

[8] Weight loss and incretin responsiveness improve glucose control independently after gastric bypass surgery [J].

Bose, Mousumi ;

Teixeira, Julio ;

Olivan, Blanca ;

Bawa, Baani ;

Arias, Sara ;

Machineni, Sriram ;

Pi-Sunyer, F. Xavier ;

Scherer, Philipp E. ;

Laferrere, Blandine .

JOURNAL OF DIABETES, 2010, 2 (01) :47-55

[9] Scintigraphic Evaluation of Gastric Emptying in Obese Patients Submitted to Sleeve Gastrectomy Compared to Normal Subjects [J].

Braghetto, Italo ;

Davanzo, Cristobal ;

Korn, Owen ;

Csendes, Attila ;

Valladares, Hector ;

Herrera, Eduardo ;

Gonzalez, Patricio ;

Papapietro, Karin .

OBESITY SURGERY, 2009, 19 (11) :1515-1521

[10]

BRUUSGAARD A, 1976, SCAND J GASTROENTERO, V11, P833

← 1 2 3 4 5 6 7 8 9 10 →