Self-protection strategies and health behaviour in patients with inflammatory rheumatic diseases during the COVID-19 pandemic: results and predictors in more than 12 000 patients with inflammatory rheumatic diseases followed in the Danish DANBIO registry

被引：47

作者：

Glintborg, Bente ^{[1
,2
,3
]}

Jensen, Dorte Vendelbo ^{[1
,4
]}

Engel, Sara ^{[1
,2
]}

Terslev, Lene ^{[2
,3
]}

Jensen, Mogens Pfeiffer ^{[2
,3
]}

Hendricks, Oliver ^{[5
,6
]}

Ostergaard, Mikkel ^{[1
,2
,3
]}

Rasmussen, Simon Horskjaer ^{[2
]}

Adelsten, Thomas ^{[7
]}

Colic, Ada ^{[7
]}

Danebod, Kamilla ^{[2
]}

Kildemand, Malene ^{[8
]}

Loft, Anne Gitte ^{[9
,10
]}

Munk, Heidi Lausten ^{[8
,11
]}

Pedersen, Jens Kristian ^{[12
]}

Ostgard, Rene Drage ^{[13
]}

Sorensen, Christian Moller ^{[14
]}

Krogh, Niels Steen ^{[15
]}

Agerbo, Jette ^{[16
]}

Ziegler, Connie ^{[16
]}

Hetland, Merete ^{[1
,2
,3
]}

机构：

[1] Rigshosp Glostrup, DANBIO, Glostrup, Denmark

[2] Rigshosp Glostrup, Copenhagen Ctr Arthrit Res COPECARE, Ctr Rheumatol & Spine Dis, Ctr Head & Orthoped, Glostrup, Denmark

[3] Univ Copenhagen, Dept Clin Med, Fac Hlth & Med Sci, Copenhagen, Denmark

[4] Gentofte Univ Hosp, Ctr Rheumatol & Spine Dis, Dept Rheumatol, Hellerup, Hovedstaden, Denmark

[5] Univ Southern Denmark, Danish Hosp Rheumat Dis, Sonderborg, Syddanmark, Denmark

[6] Univ Southern Denmark, Dept Reg Hlth Res, Odense, Syddanmark, Denmark

[7] Sjaelland Univ Hosp Koge, Dept Rheumatol, Koge, Sjaelland, Denmark

[8] Odense Univ Hosp, Dept Rheumatol, Odense, Denmark

[9] Aarhus Univ Hosp, Dept Rheumatol, Aarhus, Denmark

[10] Aarhus Univ, Dept Clin Med, Aarhus, Midtjylland, Denmark

[11] Univ Southern Denmark, Dept Clin Res, Odense, Syddanmark, Denmark

[12] Svendborg Hosp, Dept Med, Svendborg, Syddanmark, Denmark

[13] Silkeborg Reg Hosp, Diagnost Ctr, Silkeborg, Midtjylland, Denmark

[14] Reg Hosp Horsens, Dept Med, Horsens, Midtjylland, Denmark

[15] Zitelab Aps, Copenhagen, Denmark

[16] Danish Rheumatism Assoc Gigtforeningen, Copenhagen, Denmark

来源：

RMD OPEN | 2021年 / 7卷 / 01期

关键词：

epidemiology; arthritis; rheumatoid; patient reported outcome measures; outcome assessment; health care;

D O I：

10.1136/rmdopen-2020-001505

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aims In Danish patients with inflammatory rheumatic diseases to explore self-protection strategies and health behaviour including adherence to disease-modifying antirheumatic treatment (DMARD) during the initial phase of the COVID-19 pandemic and again after the reopening of the society started. Furthermore, to identify characteristics of patients with high levels of anxiety and self-isolation. Methods Patients in routine care followed prospectively in the nationwide DANBIO registry were invited to answer an online questionnaire regarding disease activity and COVID-19 infection, behaviour in March and June 2020. Responses were linked to patient data in DANBIO. Characteristics potentially associated with anxiety, self-isolation and medication adherence (gender/age/diagnosis/education/work status/comorbidity/DMARD/smoking/EQ-5D/disease activity) were explored with multivariable logistic regression analyses. Results We included 12 789 patients (8168 rheumatoid arthritis/2068 psoriatic arthritis/1758 axial spondyloarthritis/795 other) of whom 65% were women and 36% treated with biological DMARD. Self-reported COVID-19 prevalence was 0.3%. Patients reported that they were worried to get COVID-19 infection (March/June: 70%/45%) and self-isolated more than others of the same age (48%/38%). The fraction of patients who changed medication due to fear of COVID-19 were 4.1%/0.6%. Female gender, comorbidities, not working, lower education, biological treatment and poor European Quality of life, 5 dimensions were associated with both anxiety and self-isolation. Conclusion In >12 000 patients with inflammatory arthritis, we found widespread anxiety and self-isolation, but high medication adherence, in the initial phase of the COVID-19 pandemic. This persisted during the gradual opening of society during the following months. Attention to patients' anxiety and self-isolation is important during this and potential future epidemics.

引用

页数：13

共 20 条

[1] Perspectives of Patients With Rheumatic Diseases in the Early Phase ofCOVID-19 [J].