Mechanisms of disease: Age-related macular degeneration

被引：716
作者：
de Jong, Paulus T. V. M.
机构：
[1] Royal Netherlands Acad Arts & Sci, KNAW, Netherlands Inst Neurosci, Dept Ophthalmogenet, NL-1105 BA Amsterdam, Netherlands
[2] Univ Amsterdam, Acad Med Ctr, Dept Ophthalmol, NL-1105 AZ Amsterdam, Netherlands
[3] Erasmus MC, Dept Epidemiol & Biostat, Rotterdam, Netherlands
来源：
NEW ENGLAND JOURNAL OF MEDICINE | 2006年 / 355卷 / 14期
关键词：
D O I：
10.1056/NEJMra062326
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
[No abstract available]
引用
收藏
页码：1474 / 1485
页数：12
相关论文
共 127 条
[1]   Drusen in age-related macular degeneration: Pathogenesis, natural course, and laser photocoagulation-induced regression [J].
Abdelsalam, A ;
Del Priore, L ;
Zarbin, MA .
SURVEY OF OPHTHALMOLOGY, 1999, 44 (01) :1-29
[2]  
AHMED J, 1993, INVEST OPHTH VIS SCI, V34, P516
[3]   Age-related maculopathy and the impact of blue light hazard [J].
Algvere, PV ;
Marshall, J ;
Seregard, S .
ACTA OPHTHALMOLOGICA SCANDINAVICA, 2006, 84 (01) :4-15
[4]   Further evidence for an association of ABCR alleles with age-related macular degeneration [J].
Allikmets, R .
AMERICAN JOURNAL OF HUMAN GENETICS, 2000, 67 (02) :487-491
[5]   Mutation of the Stargardt disease gene (ABCR) in age-related macular degeneration [J].
Allikmets, R ;
Shroyer, NF ;
Singh, N ;
Seddon, JM ;
Lewis, RA ;
Bernstein, PS ;
Peiffer, A ;
Zabriskie, NA ;
Li, YX ;
Hutchinson, A ;
Dean, M ;
Lupski, JR ;
Leppert, M .
SCIENCE, 1997, 277 (5333) :1805-1807
[6]  
[Anonymous], 1979, RETINAL PIGMENT EPIT
[7]   Heterogeneity of the genetic risk in age-related macular disease - A population-based familial risk study [J].
Assink, JJM ;
Klaver, CCW ;
Houwing-Duistermaat, JJ ;
Wolfs, RCW ;
van Duijn, CM ;
Hofman, A ;
de Jong, PTVM .
OPHTHALMOLOGY, 2005, 112 (03) :482-487
[8]   The ε2 and ε4 alleles of the apolipoprotein gene are associated with age-related macular degeneration [J].
Baird, PN ;
Guida, E ;
Chu, DT ;
Vu, HTV ;
Guymer, RH .
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2004, 45 (05) :1311-1315
[9]   The role of oxidative stress in the pathogenesis of age-related macular degeneration [J].
Beatty, S ;
Koh, HH ;
Henson, D ;
Boulton, M .
SURVEY OF OPHTHALMOLOGY, 2000, 45 (02) :115-134
[10]   Inhibition of the ATP-driven proton pump in RPE lysosomes by the major lipofuscin fluorophore A2-E may contribute to the pathogenesis of age-related macular degeneration [J].
Bergmann, M ;
Schütt, F ;
Holz, FG ;
Kopitz, J .
FASEB JOURNAL, 2004, 18 (01) :562-+
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