Selectively targeting MYC expression with nucleic acid binding small molecules

被引:0
|
作者
Calabrese, David [1 ]
Leon, Elena [2 ]
Gaikwad, Snehal [2 ]
Chen, Xiang [3 ]
Alden, Stephanie [1 ]
Phyo, Zaw
Hewitt, William [1 ]
Hilimire, Thomas [1 ,2 ]
Walters, Kylie [3 ]
Mock, Beverly
Schneekloth, John [1 ,2 ]
机构
[1] NCI, Chem Biol Lab, Frederick, MD 21701 USA
[2] NCI, Lab Canc Biol & Genet, Frederick, MD 21701 USA
[3] NCI, Struct Biophys Lab, Frederick, MD 21701 USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
12
引用
收藏
页数:1
相关论文
共 50 条
  • [1] NALDB: nucleic acid ligand database for small molecules targeting nucleic acid
    Mishra, Subodh Kumar
    Kumar, Amit
    DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION, 2016,
  • [2] Recent Advances in Developing Small Molecules Targeting Nucleic Acid
    Wang, Maolin
    Yu, Yuanyuan
    Liang, Chao
    Lu, Aiping
    Zhang, Ge
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2016, 17 (06):
  • [3] Small molecules selectively targeting breast cancer cells
    Sakoff, J.
    Gilbert, J.
    McCluskey, A.
    EUROPEAN JOURNAL OF CANCER, 2014, 50 : 36 - 36
  • [4] Effective targeting of MYC expression with a novel nucleic acid binding (G4-quadruplex) small molecule coupled with HDAC inhibition synergizes to limit myeloma growth
    Gaikwad, Snehal M.
    Calabrese, David R.
    Leon, Elena C.
    Simmons, John K.
    Zhang, Shuling
    Michalowski, Aleksandra
    Gorjifard, Sayeh
    Phyo, Zaw
    Connors, Daniel
    Schneekloth, John S.
    Mock, Beverly A.
    CANCER RESEARCH, 2017, 77
  • [5] Small molecules targeting the intrinsically disordered oncoprotein MYC
    Castell, Alina
    Bazzar, Wesam
    Larsson, Lars-Gunnar
    EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2023, 52 (SUPPL 1): : S73 - S73
  • [6] The energetics of small molecules binding with nucleic acids
    Kostjukov, Viktor V.
    Evstigneev, Maxim P.
    JOURNAL OF CHEMICAL THERMODYNAMICS, 2019, 139
  • [7] Intercalative binding of small molecules to nucleic acids
    Graves, DE
    Velea, LM
    CURRENT ORGANIC CHEMISTRY, 2000, 4 (09) : 915 - 929
  • [8] Targeting Twist expression with small molecules
    Pei, Haixiang
    Li, Yunqi
    Liu, Mingyao
    Chen, Yihua
    MEDCHEMCOMM, 2017, 8 (02) : 268 - 275
  • [9] Novel Nucleic Acid Binding Small Molecules Discovered Using DNA-Encoded Chemistry
    Litovchick, Alexander
    Tian, Xia
    Monteiro, Michael I.
    Kennedy, Kaitlyn M.
    Guie, Marie-Aude
    Centrella, Paolo
    Zhang, Ying
    Clark, Matthew A.
    Keefe, Anthony D.
    MOLECULES, 2019, 24 (10)
  • [10] Selectively targeting cancer cells with a novel family of small molecules.
    Jaunky, D.
    Liu, J.
    Larocque, K.
    Husser, M.
    Michel, A.
    Forgione, P.
    Piekny, A. J.
    MOLECULAR BIOLOGY OF THE CELL, 2018, 29 (26)