Mycenolide A, new butenolide from a marine sediment-derived bacteriumStreptomycessp. 4054

被引：5
|
作者：
Monteiro de Oliveira, Josiane A. [1 ,2 ]
Williams, David E. [2 ]
Andersen, Raymond J. [2 ]
Sarragiotto, Maria H. [1 ]
Baldoqui, Debora C. [1 ]
机构：
[1] Univ Estadual Maringa, Dept Quim, Av Colombo 5790, BR-87020900 Maringa, Parana, Brazil
[2] Univ British Columbia, Dept Chem & Earth Ocean & Atmospher Sci, Vancouver, BC, Canada
来源：
NATURAL PRODUCT RESEARCH | 2020年 / 34卷 / 20期
基金：
加拿大自然科学与工程研究理事会;
关键词：
Streptomyces; butenolides; antimicrobial activity; METABOLITES;
D O I：
10.1080/14786419.2019.1597351
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Streptomycessp. 4054, isolated from marine sediments, produced a new butenolide, mycenolide A (1), along with five known butenolide derivatives (2-6). The structures of the compounds were established based on 1D- and 2D-NMR spectroscopic analysis, circular dichroism, and mass spectrometry data. The antimicrobial activity of the crude extract of the marine bacteriaStreptomycessp. 4054 was evaluated, showing good results againstBacillus subtilisand MRSA.
引用
收藏
页码：2986 / 2989
页数：4
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