Nitrofurantoin-induced lung disease: Two cases demonstrating resolution of apparently irreversible CT abnormalities

被引：21

作者：

Sheehan, RE

Wells, AU

Milne, DG

Hansell, DM

机构：

[1] Royal Brompton Hosp, Dept Radiol, London SW3 6NP, England

[2] Royal Brompton Hosp, Dept Resp Med, London SW3 6NP, England

来源：

JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY | 2000年 / 24卷 / 02期

关键词：

drugs; toxicity; computed tomography; lungs; diseases;

D O I：

10.1097/00004728-200003000-00013

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A reticular pattern on high resolution CT (HRCT) invariably represents significant lung pathology and is the dominant feature of irreversible fibrosis. We present two cases of nitrofurantoin-induced pulmonary toxicity in which the initial HRCT showed a widespread reticular pattern and associated distortion of the lung parenchyma, thought to represent established fibrosis. Follow-up HRCT scans after withdrawal of the drug showed resolution of this supposedly irreversible pattern.

引用

页码：259 / 261

页数：3

共 16 条

[1]

BENZAQUENFORNER H, 1999, EUR RESP J S30, V14, P501

[2] HIGH-RESOLUTION CT OF PARENCHYMAL LUNG-DISEASE - PRECISE CORRELATION WITH HISTOLOGIC-FINDINGS [J].