Nitrofurantoin-induced lung disease: Two cases demonstrating resolution of apparently irreversible CT abnormalities

被引：21
作者：
Sheehan, RE
Wells, AU
Milne, DG
Hansell, DM
机构：
[1] Royal Brompton Hosp, Dept Radiol, London SW3 6NP, England
[2] Royal Brompton Hosp, Dept Resp Med, London SW3 6NP, England
来源：
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY | 2000年 / 24卷 / 02期
关键词：
drugs; toxicity; computed tomography; lungs; diseases;
D O I：
10.1097/00004728-200003000-00013
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
A reticular pattern on high resolution CT (HRCT) invariably represents significant lung pathology and is the dominant feature of irreversible fibrosis. We present two cases of nitrofurantoin-induced pulmonary toxicity in which the initial HRCT showed a widespread reticular pattern and associated distortion of the lung parenchyma, thought to represent established fibrosis. Follow-up HRCT scans after withdrawal of the drug showed resolution of this supposedly irreversible pattern.
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页码：259 / 261
页数：3
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