There were 63,162 adult patients receiving renal replacement therapy (RRT) in the UK on 31 December 2016, an absolute increase of 3.1% from 2015. The actual number of patients increased by 0.9% for haemodialysis (HD), 5.1% for those with a functioning transplant and less than 0.1% for peritoneal dialysis (PD). The UK adult prevalence of RRT was 962 per million population (pmp). The reported prevalence in 2000 was 523 pmp. The number of patients receiving home HD increased slightly from 1,175 patients in 2015 to 1,256 patients in 2016. In 2016 the median age of prevalent patients was 59 years (HD 67 years, PD 64 years, transplant 54 years). In 2000 the median age was 55 years (HD 63 years, PD 58 years, transplant 48 years). The percentage of RRT patients aged greater than 75 years in 2016 was 16.0%. For all ages, RRT prevalence in men exceeded that in women, peaking in age group 80-84 years at 3,072 pmp in men and in the 70-74 years age group at 1,657 pmp in women. The most common identifiable renal diagnosis was glomerulonephritis (19%), followed by diabetes (17%), other (17%) and aetiology uncertain (15%). Transplantation continued as the most common treatment modality (54%), HD was used in 40% and PD in 6% of RRT patients.