Mitochondria-targeted colorimetric and fluorescent probes for hypochlorite and their applications for in vivo imaging

被引：153

作者：

Hou, Ji-Ting ^{[1
]}

Wu, Ming-Yu ^{[1
]}

Li, Kun ^{[1
,2
]}

Yang, Jin ^{[1
]}

Yu, Kang-Kang ^{[1
]}

Xie, Yang-Mel ^{[2
]}

Yu, Xiao-Qi ^{[1
]}

机构：

[1] Sichuan Univ, Coll Chem, Minist Educ, Key Lab Green Chem & Technol, Chengdu 610064, Peoples R China

[2] Sichuan Univ, West China Hosp, West China Med Sch, State Key Lab Biotherapy, Chengdu 610041, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 63期

基金：

美国国家科学基金会;

关键词：

INDUCED HOCL PRODUCTION; LIVING CELLS; SELECTIVE DETECTION; RATIONAL DESIGN; TURN-ON; ACID; BODIPY; OXIDATION; SENSOR; DYES;

D O I：

10.1039/c4cc02673j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two mitochondria-targeted real-time probes were presented, which could selectively respond to hypochlorite over other ROS. Meanwhile, the "off-on" probes could be successfully applied in the in vivo imaging of hypochlorite in living mice.

引用

页码：8640 / 8643

页数：4

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