Fluctuation of Hepatic Focal Nodular Hyperplasia Size with Oral Contraceptives Use

被引：3

作者：

Fukahori, Susumu ^{[1
,2
]}

Kawano, Tetsuya ^{[1
,3
]}

Obase, Yasushi ^{[1
]}

Umeyama, Yasuhiro ^{[1
,2
]}

Sugasaki, Nanae ^{[1
,2
]}

Kinoshita, Akitoshi ^{[1
,2
]}

Fukushima, Chizu ^{[1
]}

Yamakawa, Masaki ^{[4
]}

Omagari, Katsuhisa ^{[5
]}

Mukae, Hiroshi ^{[1
]}

机构：

[1] Nagasaki Univ, Dept Resp Med, Grad Sch Biomed Sci, Nagasaki, Japan

[2] Nagasaki Prefecture Shimabara Hosp, Dept Internal Med, Nagasaki, Japan

[3] Nagasaki Univ Hosp, Smoking Control Ctr, Nagasaki, Japan

[4] Nagasaki Natl Hosp, Dept Internal Med, Nagasaki, Japan

[5] Univ Nagasaki, Fac Nursing & Nutr, Dept Nutr Sci, Siebold Campus, Nagasaki, Japan

来源：

AMERICAN JOURNAL OF CASE REPORTS | 2019年 / 20卷

关键词：

Contraceptives; Oral; Hormonal; Focal Nodular Hyperplasia; Gonadal Steroid Hormones; HEPATOCELLULAR ADENOMA; LIVER-TUMORS;

D O I：

10.12659/AJCR.916398

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective: Rare disease Background: Focal nodular hyperplasia (FNH) of the liver is a rare benign nodular lesion that arises in women of reproductive age. Although a role of female hormones has been suggested, their influence on the course of FNH has remained controversial. Case Report: A 44-year-old woman with a 12-year history of oral contraceptive use was referred to our hospital for examination of an asymptomatic liver mass (3 cm in diameter) identified by computed tomography. We diagnosed FNH using imaging methods and fine-needle biopsy. Oral contraceptives were discontinued because the mass increased over a period of 21 months. Four months later, the mass had decreased in size, indicating that FNH can spontaneously regress when oral contraceptives are discontinued. Conclusions: Discontinuation of oral contraceptives use can reduce the size of FNH, as in this case.

引用

页码：1124 / 1127

页数：4

共 15 条

[1] Management of focal nodular hyperplasia and hepatocellular adenoma in young women: A series of 41 patients with clinical, radiological, and pathological correlations [J].