Role of mitogen-activated protein kinases in ischemia and reperfusion injury - The good and the bad

被引:106
作者
Abe, J [1 ]
Baines, CP [1 ]
Berk, BC [1 ]
机构
[1] Univ Rochester, Cardiol Unit, Cardiovasc Res Ctr, Rochester, NY 14642 USA
关键词
ischemia/reperfusion; mitogen-activated protein kinase; apoptosis; cardiomyocyte;
D O I
10.1161/01.RES.86.6.607
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:607 / 609
页数:3
相关论文
共 27 条
[11]   Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor [J].
Kato, Y ;
Tapping, RI ;
Huang, S ;
Watson, MH ;
Ulevitch, RJ ;
Lee, JD .
NATURE, 1998, 395 (6703) :713-716
[12]   Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase [J].
Kummer, JL ;
Rao, PK ;
Heidenreich, KA .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (33) :20490-20494
[13]   Cyclin D1 expression is regulated positively by the p42/p44(MAPK) and negatively by the p38/HOG(MAPK) pathway [J].
Lavoie, JN ;
LAllemain, G ;
Brunet, A ;
Muller, R ;
Pouyssegur, J .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (34) :20608-20616
[14]   PRIMARY STRUCTURE OF BMK1 - A NEW MAMMALIAN MAP KINASE [J].
LEE, JD ;
ULEVITCH, RJ ;
HAN, JH .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1995, 213 (02) :715-724
[15]   Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion [J].
Ma, XL ;
Kumar, S ;
Gao, F ;
Louden, CS ;
Lopez, BL ;
Christopher, TA ;
Wang, CL ;
Lee, JC ;
Feuerstein, GZ ;
Yue, TL .
CIRCULATION, 1999, 99 (13) :1685-1691
[16]  
Martin JL, 1997, CIRCULATION, V96, P4343
[17]   Ischemic preconditioning activates MAPKAPK2 in the isolated rabbit heart - Evidence for involvement of p38 MAPK [J].
Nakano, A ;
Baines, CP ;
Kim, SO ;
Pelech, SL ;
Downey, JM ;
Cohen, MV ;
Critz, SD .
CIRCULATION RESEARCH, 2000, 86 (02) :144-151
[18]   Apoptotic myocytes in infarct area in rabbit hearts may be oncotic myocytes with DNA fragmentation - Analysis by immunogold electron microscopy combined with in situ nick end-labeling [J].
Ohno, M ;
Takemura, G ;
Ohno, A ;
Misao, J ;
Hayakawa, Y ;
Minatoguchi, S ;
Fujiwara, T ;
Fujiwara, H .
CIRCULATION, 1998, 98 (14) :1422-1430
[19]  
Saraste A, 1997, CIRCULATION, V95, P320
[20]   Stress-responsive mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogen-activated protein kinases) in the myocardium [J].
Sugden, PH ;
Clerk, A .
CIRCULATION RESEARCH, 1998, 83 (04) :345-352