Synthesis of Highly Functionalized Diaryl Ethers by Copper-Mediated O-Arylation of Phenols using Trivalent Arylbismuth Reagents

被引：33

作者：

Crifar, Cynthia ^{[1
]}

Petiot, Pauline ^{[1
]}

Ahmad, Tabinda ^{[1
]}

Gagnon, Alexandre ^{[1
]}

机构：

[1] Univ Quebec, Dept Chim, Montreal, PQ H3C 3P8, Canada

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2014年 / 20卷 / 10期

基金：

加拿大自然科学与工程研究理事会;

关键词：

copper catalysis; functionalized diaryl ethers; O-arylation; phenols; triarylbismuthanes; PENTAVALENT ORGANOBISMUTH REAGENTS; LIGAND COUPLING REACTIONS; C-N; PHENYLATION; CHEMISTRY; ALCOHOLS; DERIVATIVES; BISMUTH(V); ENOLS; ACIDS;

D O I：

10.1002/chem.201303684

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Highly functionalized diaryl ethers were prepared by copper(II) acetate mediated O-arylation reaction of phenols using trivalent organobismuthanes. The reaction is performed under simple conditions and tolerates a wide diversity of functional groups on the phenol and on the organobismuth reagent. Substoichiometric amounts of catalyst can be used by performing the reaction under an oxygen atmosphere. The N-arylation of pyridones is also reported.

引用

页码：2755 / 2760

页数：6

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