Clinical and Neuroimaging Findings in Neonatal Herpes Simplex Virus Infection

被引：14
|
作者：
Bajaj, Monika [1 ]
Mody, Swati [2 ]
Natarajan, Girija [1 ]
机构：
[1] Wayne State Univ, Carman & Ann Dept Pediat, Detroit, MI USA
[2] Wayne State Univ, Dept Radiol, Detroit, MI USA
来源：
JOURNAL OF PEDIATRICS | 2014年 / 165卷 / 02期
关键词：
TYPE-2; ENCEPHALITIS; VIDARABINE THERAPY; IMAGING FINDINGS; CALIFORNIA; CHILDREN;
D O I：
10.1016/j.jpeds.2014.04.046
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
In a retrospective review of infants with neonatal herpes simplex virus disease (n = 29), we found bilateral multilobar (n = 8), pontine (n = 3), thalamic (n = 6), and internal capsule and corticospinal tract (n = 5) involvement on magnetic resonance imaging (MRI). Diffusion-weighted imaging (n = 6) performed early revealed additional involvement than detected by conventional MRI. Neurodevelopmental sequelae were correlated with MRI abnormalities. Our findings demonstrate that MRI, including diffusion-weighted imaging, is a valuable prognostic adjunct in neonatal herpes simplex virus disease.
引用
收藏
页码：404 / U253
页数：5
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