Clinical and Neuroimaging Findings in Neonatal Herpes Simplex Virus Infection

被引：15

作者：

Bajaj, Monika ^{[1
]}

Mody, Swati ^{[2
]}

Natarajan, Girija ^{[1
]}

机构：

[1] Wayne State Univ, Carman & Ann Dept Pediat, Detroit, MI USA

[2] Wayne State Univ, Dept Radiol, Detroit, MI USA

来源：

JOURNAL OF PEDIATRICS | 2014年 / 165卷 / 02期

关键词：

TYPE-2; ENCEPHALITIS; VIDARABINE THERAPY; IMAGING FINDINGS; CALIFORNIA; CHILDREN;

D O I：

10.1016/j.jpeds.2014.04.046

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

In a retrospective review of infants with neonatal herpes simplex virus disease (n = 29), we found bilateral multilobar (n = 8), pontine (n = 3), thalamic (n = 6), and internal capsule and corticospinal tract (n = 5) involvement on magnetic resonance imaging (MRI). Diffusion-weighted imaging (n = 6) performed early revealed additional involvement than detected by conventional MRI. Neurodevelopmental sequelae were correlated with MRI abnormalities. Our findings demonstrate that MRI, including diffusion-weighted imaging, is a valuable prognostic adjunct in neonatal herpes simplex virus disease.

引用

页码：404 / U253

页数：5

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