Protein-protein interactions: PDZ domain networks

被引：231

作者：

Fanning, AS ^{[1
]}

Anderson, JM ^{[1
]}

机构：

[1] YALE UNIV,SCH MED,DEPT CELL BIOL,NEW HAVEN,CT 06520

来源：

CURRENT BIOLOGY | 1996年 / 6卷 / 11期

关键词：

D O I：

10.1016/S0960-9822(96)00737-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

PDZ domains can dimerize or bind to the carboxyl termini of unrelated proteins. Crystallographic studies demonstrate the structural basis for these interactions, which contribute to the ability of PDZ domains to create networks associated with the plasma membrane.

引用

收藏

页码：1385 / 1388

页数：4

相关论文

共 16 条

[1] Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha 1-syntrophin mediated by PDZ domains [J].

Brenman, JE ;

Chao, DS ;

Gee, SH ;

McGee, AW ;

Craven, SE ;

Santillano, DR ;

Wu, ZQ ;

Huang, F ;

Xia, HH ;

Peters, MF ;

Froehner, SC ;

Bredt, DS .

CELL, 1996, 84 (05) :757-767

[2]

CABRAL JH, 1996, NATURE, V384, P649

[3] THE RAT-BRAIN POSTSYNAPTIC DENSITY FRACTION CONTAINS A HOMOLOG OF THE DROSOPHILA DISKS-LARGE TUMOR SUPPRESSOR PROTEIN [J].

CHO, KO ;

HUNT, CA ;

KENNEDY, MB .

NEURON, 1992, 9 (05) :929-942

[4] MOLECULAR AND FUNCTIONAL-ANALYSIS OF A LYMPHOCYTE CHEMOATTRACTANT FACTOR - ASSOCIATION OF BIOLOGIC FUNCTION WITH CD4 EXPRESSION [J].

CRUIKSHANK, WW ;

CENTER, DM ;

NISAR, N ;

WU, MN ;

NATKE, B ;

THEODORE, AC ;

KORNFELD, H .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (11) :5109-5113

[5] Crystal structures of a complexed and peptide-free membrane protein-binding domain: Molecular basis of peptide recognition by PDZ [J].

Doyle, DA ;

Lee, A ;

Lewis, J ;

Kim, E ;

Sheng, M ;

MacKinnon, R .

CELL, 1996, 85 (07) :1067-1076

[6]

Fanning AS, 1996, CURR TOP MEMBR, V43, P211

[7] Peptide-surface association: The case of PDZ and PTB domains [J].

Harrison, SC .

CELL, 1996, 86 (03) :341-343

[8]

Hata Y, 1996, J NEUROSCI, V16, P2488

[9] Heteromultimerization and NMDA receptor-clustering activity of chapsyn-110, a member of the PSD-95 family of proteins [J].

Kim, E ;

Cho, KO ;

Rothschild, A ;

Sheng, M .

NEURON, 1996, 17 (01) :103-113

[10] CLUSTERING OF SHAKER-TYPE K+ CHANNELS BY INTERACTION WITH A FAMILY OF MEMBRANE-ASSOCIATED GUANYLATE KINASES [J].

KIM, E ;

NIETHAMMER, M ;

ROTHSCHILD, A ;

JAN, YN ;

SHENG, M .

NATURE, 1995, 378 (6552) :85-88