Protein-protein interactions: PDZ domain networks

被引:231
|
作者
Fanning, AS [1 ]
Anderson, JM [1 ]
机构
[1] YALE UNIV,SCH MED,DEPT CELL BIOL,NEW HAVEN,CT 06520
关键词
D O I
10.1016/S0960-9822(96)00737-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
PDZ domains can dimerize or bind to the carboxyl termini of unrelated proteins. Crystallographic studies demonstrate the structural basis for these interactions, which contribute to the ability of PDZ domains to create networks associated with the plasma membrane.
引用
收藏
页码:1385 / 1388
页数:4
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