Use of Sublingual Immunotherapy for Aeroallergens in Children with Asthma

被引：5
|
作者：
Caffarelli, Carlo [1 ]
Mastrorilli, Carla [2 ]
Procaccianti, Michela [1 ]
Santoro, Angelica [1 ]
机构：
[1] Univ Parma, Azienda Osped, Dipartimento Med & Chirurg, Clin Pediat, I-43126 Parma, Italy
[2] Osped Pediat Giovanni XXIII, UO Pediat & Pronto Soccorso, Azienda Osped, Univ Consorziale Policlin, I-70126 Bari, Italy
来源：
JOURNAL OF CLINICAL MEDICINE | 2020年 / 9卷 / 10期
关键词：
asthma; children; efficacy; house dust mite; pollen allergy; rhinitis; safety; sublingual immunotherapy; HOUSE-DUST MITE; ALLERGEN-SPECIFIC IMMUNOTHERAPY; PLACEBO-CONTROLLED EVALUATION; DOUBLE-BLIND; SWALLOW IMMUNOTHERAPY; SUBCUTANEOUS IMMUNOTHERAPY; RESPIRATORY ALLERGY; INHALANT ALLERGENS; PEDIATRIC-PATIENTS; CLINICAL-EFFICACY;
D O I：
10.3390/jcm9103381
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Asthma is a heterogeneous disease that in children is often allergen-driven with a type 2 inflammation. Sublingual immunotherapy represents an important progress in the use of personalized medicine in children with allergic asthma. It is a viable option for house dust mite-driven asthma and in subjects with the asthma associated with allergic rhinitis. The use and indications for isolated asthma caused by other allergens are still controversial owing to heterogeneity of commercially available products and methodological limitations of studies in children. Nevertheless, most studies and meta-analyses found the efficacy of sublingual immunotherapy. Sublingual immunotherapy is safe but cannot be recommended in children with uncontrolled asthma.
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页码：1 / 16
页数：16
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