Synthesis of large generation poly(propyl ether imine) (PETIM) dendrimers

被引：38

作者：

Jayamurugan, Govindasamy ^{[1
]}

Jayaraman, Narayanaswamy ^{[1
]}

机构：

[1] Indian Inst Sci, Dept Organ Chem, Bangalore 560012, Karnataka, India

来源：

TETRAHEDRON | 2006年 / 62卷 / 41期

关键词：

dendrimers; iterative synthesis; Michael addition; Raney cobalt;

D O I：

10.1016/j.tet.2006.07.094

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Large generation poly(propyl ether imine) (PETIM) dendrimers are synthesized in iterative synthetic cycles of two reductions and two Michael addition reactions. Dendrimers up to sixth generation, containing up to 128 peripheral functionalities, are synthesized. Growth of the PETIM dendrimers, possessing a tertiary amine as the branch juncture and an ether as the linker component, is assessed systematically by routine spectroscopic methods. The peripheries of these dendrimers possess either alcohols, amines, carboxylic acids, esters, or nitriles, thereby opening up possibilities for varied studies involving PETIM dendrimers. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：9582 / 9588

页数：7

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